Ignite Creation Date:
2024-05-06 @ 8:11 PM
Last Modification Date:
2024-10-26 @ 3:22 PM
Study NCT ID:
NCT06287320
Status:
RECRUITING
Last Update Posted:
2024-03-01
First Post:
2024-02-23
Brief Title:
The Predictive Biomarkers in Patients With Locally Advanced Non-small Cell Lung Cancer
Sponsor:
Cancer Institute and Hospital Chinese Academy of Medical Sciences
Organization:
Cancer Institute and Hospital Chinese Academy of Medical Sciences
Study Overview
Official Title:
The Peripheral Blood Lymphocyte Subsets as Predicative Biomarkers Reflecting the Efficacy and Toxicity in Patients With Locally Advanced Non-small Cell Lung Cancer Received Chemoradiotherapy With or Without Immunotherapy
Status:
RECRUITING
Status Verified Date:
2024-01
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study is a prospective cohort study to evaluate the peripheral blood lymphocyte subsets as predicative biomarkers reflecting the efficacy and toxicity in patients with locally advanced non-small cell lung cancer NSCLC received chemoradiotherapy CRT with or without immune checkpoint inhibitors ICIs
Detailed Description:
All patients had a pathologically confirmed locally advanced NSCLC according to the 8th AJCC staging system and received definitive radiotherapy concurrently or sequentially combined with platinum-based doublet chemotherapy The peripheral blood samples at various time points including before radiation 4 weeks after beginning of radiation the end of radiation 1 month post radiation and 1 month post consolidation immunotherapy were collected for lymphocyte subsets detection
The subjects will be divided into two groups according to whether patients received ICIs namely NSCLC patients received CRT plus ICIs and NSCLC patients received CRT
The subjects will be divided into two groups according to whether patients received ICIs namely NSCLC patients received CRT plus ICIs and NSCLC patients received CRT
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None