Ignite Creation Date:
2024-05-06 @ 8:11 PM
Last Modification Date:
2024-10-26 @ 3:22 PM
Study NCT ID:
NCT06288256
Status:
RECRUITING
Last Update Posted:
2024-03-01
First Post:
2024-02-23
Brief Title:
Neurocognitive and Genomic Predictors of Persistent Pain and Opioid Misuse After Spine Surgery
Sponsor:
Icahn School of Medicine at Mount Sinai
Organization:
Icahn School of Medicine at Mount Sinai
Study Overview
Official Title:
Neurocognitive and Genomic Predictors of Persistent Pain and Opioid Misuse After Spine Surgery
Status:
RECRUITING
Status Verified Date:
2024-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Having spine surgery and recovery is a vulnerable period when opioid naive patients may transition into long-term use of opioids and when previously opioid tolerant patients may be at risk to continue towards long-term opioid use and dependence However little is known about risk for developing opioid misuse taking opioids differently than indicated or prescribed and later OUD This study addresses the question of whether behavior cognitive features and genomic markers can predict misuse of opioids persistent pain and disability in individuals after spine surgery
To determine if impulsivity inhibitory control drug choice andor cognitive distortions predict opioid misuse and disability in spine surgery patients with differential gene expression
This is a prospective observational longitudinal study characterizing behavioral phenotypes in adults undergoing spine surgery using both patient-reported survey measures cognitive testing and blood sampling Outcome measures include correlations between impulsivity measures opioid drug choice responses and cognitive distortion scores and opioid misuse with spine related disability and gene expression counts
To determine if impulsivity inhibitory control drug choice andor cognitive distortions predict opioid misuse and disability in spine surgery patients with differential gene expression
This is a prospective observational longitudinal study characterizing behavioral phenotypes in adults undergoing spine surgery using both patient-reported survey measures cognitive testing and blood sampling Outcome measures include correlations between impulsivity measures opioid drug choice responses and cognitive distortion scores and opioid misuse with spine related disability and gene expression counts
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
False
Is an FDA AA801 Violation?:
None