Ignite Creation Date:
2024-05-06 @ 8:12 PM
Last Modification Date:
2024-10-26 @ 3:23 PM
Study NCT ID:
NCT06298370
Status:
RECRUITING
Last Update Posted:
2024-03-07
First Post:
2024-02-03
Brief Title:
The Efficacy of Combined Intrathecal Morphine and PENG Block on Postoperative Pain in Hip Arthroplasty
Sponsor:
Bezmialem Vakif University
Organization:
Bezmialem Vakif University
Study Overview
Official Title:
The Efficacy of Combined Intrathecal Morphine and Pericapsular Nerve Group PENG Block on Postoperative Pain and Recovery Quality in Anterior Hip Arthroplasty A Prospective Double-blind Randomized Clinical Trial
Status:
RECRUITING
Status Verified Date:
2024-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
PENG
Brief Summary:
This study aims to compare the postoperative 48-hour period in terms of morphine consumption postoperative pain and quality of recovery scores by combining the Pericapsular Nerve Group PENG block with low-dose intrathecal morphine in hip arthroplasty as opposed to PENG alone and intrathecal morphine alone
Detailed Description:
Effective postoperative pain control in hip surgeries can reduce complications and improve postoperative care Multimodal analgesic techniques in postoperative pain management are employed to synergistically target different nociceptive mechanisms Combining peripheral nerve blocks with low-dose intrathecal opioids can decrease the systemic opioid dose Additionally side effects associated with opioids such as sedation respiratory depression nausea vomiting rash and urinary retention can be mitigated by the combination with peripheral nerve blocks
The addition of Pericapsular Nerve Group PENG block to a multimodal analgesia regimen has been shown to significantly enhance the quality of recovery and reduce opioid consumption in patients undergoing hip arthroplasty
The Quality of Recovery QoR-15 developed and validated by Stark et al in 2013 is a recovery scale indicating postoperative recovery quality It includes 15 questions assessing pain physical comfort physical independence psychological support and emotional state providing a score between 0 and 150 where a higher score indicates better recovery quality
In anterior hip surgeries it is anticipated that spinal anesthesia combined with PENG block and low-dose intrathecal morphine will result in lower postoperative morphine consumption and pain scores compared to PENG alone and intrathecal morphine alone over the first 48 hours Furthermore it is expected that the quality of recovery QoR-15 score will be higher providing patients with a longer pain-free period early mobilization and improved recovery quality
The addition of Pericapsular Nerve Group PENG block to a multimodal analgesia regimen has been shown to significantly enhance the quality of recovery and reduce opioid consumption in patients undergoing hip arthroplasty
The Quality of Recovery QoR-15 developed and validated by Stark et al in 2013 is a recovery scale indicating postoperative recovery quality It includes 15 questions assessing pain physical comfort physical independence psychological support and emotional state providing a score between 0 and 150 where a higher score indicates better recovery quality
In anterior hip surgeries it is anticipated that spinal anesthesia combined with PENG block and low-dose intrathecal morphine will result in lower postoperative morphine consumption and pain scores compared to PENG alone and intrathecal morphine alone over the first 48 hours Furthermore it is expected that the quality of recovery QoR-15 score will be higher providing patients with a longer pain-free period early mobilization and improved recovery quality
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
False
Is an FDA AA801 Violation?:
None