Ignite Creation Date:
2024-05-06 @ 8:14 PM
Last Modification Date:
2024-10-26 @ 3:23 PM
Study NCT ID:
NCT06308484
Status:
RECRUITING
Last Update Posted:
2024-03-13
First Post:
2024-02-26
Brief Title:
Neuromodulation and Mindfulness Patients With AUD
Sponsor:
Charite University Berlin Germany
Organization:
Charite University Berlin Germany
Study Overview
Official Title:
Neuromodulation and Mindfulness as Therapeutic Treatment in Detoxified Patients With AUD
Status:
RECRUITING
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Our primary objective is to integrate tVNS and mindfulness meditation within a structured mindfulness-based relapse prevention MBRP program for detoxified alcohol-dependent patients AD We aim to determine whether neuromodulation can enhance mindfulness-based relapse prevention compared to mindfulness practice alone In this context we will investigate potential changes in the interaction of top-down control and cue reactivity as well as assess the severity of AUD Measurements of drinking behavior cravings and abstinence rates will be conducted up to three months post-treatment Our second objective is to examine the causal role of frontal midline theta oscillations FMΘ in MBRP and cognitive control To achieve this we will first establish closed-loop amplitude-modulated transcranial alternating current stimulation CLAM-tACS to selectively modulate FMΘ oscillations during MBRP meditation exercises in AUD patients 2
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None