Ignite Creation Date:
2024-05-06 @ 8:14 PM
Last Modification Date:
2024-10-26 @ 3:23 PM
Study NCT ID:
NCT06305455
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-03-12
First Post:
2024-03-05
Brief Title:
Resistance Profile of Escherichia Coli in Infections of Community Origin The Importance of Antimicrobial Stewardship
Sponsor:
José Raimundo Araujo de Azevedo
Organization:
Hospital Sao Domingos
Study Overview
Official Title:
Change in the Resistance Profile of Escherichia Coli in Infections of Community Origin The Importance of Antimicrobial Stewardship
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The main objective of the study is to describe the antimicrobial resistance profile of E coli isolated in patients from the community - defined as those with cultures collected within 48 hours of hospital admission - and admitted to the intensive care unit
Detailed Description:
Background The growing antimicrobial resistance in bacterial pathogens represents a severe public health problem Isolation of Escherichia coli ESBL has been identified more frequently over the years due to the worldwide dissemination of strains with this phenotypic profile The ICU has a fully functioning Antimicrobial Stewardship team with data managed daily Thus the investigators identified increasing E coli ESBL isolates resistant to standard empiric antimicrobial therapy in community-based severe infections
Purpose The choice of empirical antimicrobial therapy is an increasingly present challenge in clinical practice often determining the outcome of critically ill patients As this is a highly relevant topic in managing this patient profile antimicrobial stewardship protocols are essential in health services enabling continuous community monitoring of emerging resistance profiles The justification for this study is based on the possibility of adding knowledge on the topic aiming to add to the global theoretical collection and alert about the locoregional occurrence of changes in the bacterial resistance profile
Objectives The main objective of the study is to describe the antimicrobial resistance profile of E coli isolated in patients from the community - defined as those with cultures collected within 48 hours of hospital admission - and admitted to the ICU
Purpose The choice of empirical antimicrobial therapy is an increasingly present challenge in clinical practice often determining the outcome of critically ill patients As this is a highly relevant topic in managing this patient profile antimicrobial stewardship protocols are essential in health services enabling continuous community monitoring of emerging resistance profiles The justification for this study is based on the possibility of adding knowledge on the topic aiming to add to the global theoretical collection and alert about the locoregional occurrence of changes in the bacterial resistance profile
Objectives The main objective of the study is to describe the antimicrobial resistance profile of E coli isolated in patients from the community - defined as those with cultures collected within 48 hours of hospital admission - and admitted to the ICU
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None