Ignite Creation Date:
2024-05-06 @ 8:14 PM
Last Modification Date:
2024-10-26 @ 3:23 PM
Study NCT ID:
NCT06305221
Status:
RECRUITING
Last Update Posted:
2024-05-09
First Post:
2024-03-03
Brief Title:
Effect of Opioid-free Analgesia and Anesthesia on the Quality of Postoperative Recovery and Nausea Vomit in Patients Receiving Laparoscopic Sleeve Gastrectomy
Sponsor:
Beijing Friendship Hospital
Organization:
Beijing Friendship Hospital
Study Overview
Official Title:
Effect of Opioid-free Analgesia and Anesthesia on the Quality of Postoperative Recovery and Nausea Vomit in Patients Receiving Laparoscopic Sleeve Gastrectomy
Status:
RECRUITING
Status Verified Date:
2024-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of the intraoperative use of opioids is to reduce the amount of sedative medication and to ensure effective analgesia But pain is an unpleasant sensory and emotional experience a cognitive perception that cannot occur with sufficient depth of anesthesia even without opioids So a more reasonable explanation for analgesia should be anti-nociception and the resulting inhibition of the response to surgical stress Since multiple mediators are involved in nociceptive pathways antinociception can also be acquired through multiple mechanisms However there is no single ideal harm drug to replace opioids which often requires two or more drugs to meet clinical needs While regional block attenuates the stress response to surgery and sympathetic activation because of afferents to block nociceptive stimuli and has an important role in the implementation of OFA Combined with the clinical characteristics of the LSG investigators developed the transverse abdominis fascia block transversus abdominis plane TAP in combination with esketamine esketamine dexmedetomidine dexmedetomidine DEX of opioid-free anesthesia opioid free anesthesia OFA and the analgesic regimen TEDOFA Reduce patient pain scores nausea and vomiting after LSG based on perfect analgesia and adequate anti-sympathetic response As well as the other complications Promote the accelerated postoperative recovery of patients undergoing LSG And reduce the incidence and severity of postoperative chronic pain
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None