Ignite Creation Date:
2024-05-06 @ 8:15 PM
Last Modification Date:
2024-10-26 @ 3:23 PM
Study NCT ID:
NCT06300853
Status:
RECRUITING
Last Update Posted:
2024-03-08
First Post:
2024-03-06
Brief Title:
Understanding Adaptive Immune Response After COVID-19 Vaccination Boosters to Improve Vaccination Strategies in Vulnerable Groups
Sponsor:
IRCCS Sacro Cuore Don Calabria di Negrar
Organization:
IRCCS Sacro Cuore Don Calabria di Negrar
Study Overview
Official Title:
Understanding Adaptive Immune Response Elicited After COVID-19 Vaccination Boosters to Improve Vaccination Strategies in Vulnerable Groups
Status:
RECRUITING
Status Verified Date:
2024-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
COVaxFragile
Brief Summary:
This is an experimental study without drug and device non-profit single-center
The general objective of the project is to study how the adaptive immune response evolves against SARS-CoV-2 with repeated vaccination boosters and infections also in relation to the evolution of variations This study will be relevant to frail populations who are the main targets of repeated vaccinations Our project will benefit from the availability of a highly cohort characterized of vaccinated people including cancer patients and elderly people with prospective collection of samples for an in-depth evaluation of the evolution of the immune response with repeated exposure to doses of infection or vaccine As part of the study analyzes will be carried out on samples of patients enrolled in a manner prospective at the oncology departments of the IRCCS Medical Oncology Department of Radiotherapy advanced oncology and nuclear medicine and elderly patients residing in retirement homes of the IRCCS Patients will also be asked for consent to store any residual samples in the Tropica DITM Biobank
The general objective of the project is to study how the adaptive immune response evolves against SARS-CoV-2 with repeated vaccination boosters and infections also in relation to the evolution of variations This study will be relevant to frail populations who are the main targets of repeated vaccinations Our project will benefit from the availability of a highly cohort characterized of vaccinated people including cancer patients and elderly people with prospective collection of samples for an in-depth evaluation of the evolution of the immune response with repeated exposure to doses of infection or vaccine As part of the study analyzes will be carried out on samples of patients enrolled in a manner prospective at the oncology departments of the IRCCS Medical Oncology Department of Radiotherapy advanced oncology and nuclear medicine and elderly patients residing in retirement homes of the IRCCS Patients will also be asked for consent to store any residual samples in the Tropica DITM Biobank
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None