Ignite Creation Date:
2024-05-06 @ 8:15 PM
Last Modification Date:
2024-10-26 @ 3:23 PM
Study NCT ID:
NCT06313580
Status:
RECRUITING
Last Update Posted:
2024-03-20
First Post:
2024-01-03
Brief Title:
Spices for Cultivating a Healthy Gut Microbiome and Cardiometabolic Profile
Sponsor:
University of Alabama Tuscaloosa
Organization:
University of Alabama Tuscaloosa
Study Overview
Official Title:
Spices for Cultivating a Healthy Gut Microbiome and Cardiometabolic Profile the SPICE Study
Status:
RECRUITING
Status Verified Date:
2024-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Among food products receiving attention for prebiotic functionality spices represent a flavorful vehicle for cultivating a healthy gut microbiota As the required doses of spice-derived polyphenols to elicit prebiotic and systemic metabolic effects are not well-characterized additional research is warranted Thus the investigators propose to use a food-first synbiotic prebiotic probiotic approach to examine alterations in the gut microbiota pre- and post-interventionplacebo and their relationship with systemic cardiometabolic effects mediated by short chain fatty acids SCFA and gut-derived metabolites
Detailed Description:
Study will be conducted as a single blind randomized crossover design with a 4-week arm placebo or control followed by a 2-week washout period and another 4-week arm placebo or control
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None