Ignite Creation Date:
2024-05-06 @ 8:16 PM
Last Modification Date:
2024-10-26 @ 3:24 PM
Study NCT ID:
NCT06315933
Status:
RECRUITING
Last Update Posted:
2024-03-18
First Post:
2024-03-12
Brief Title:
Anesthesia Neurodevelopmental Impact in Congenital Scoliosis Children
Sponsor:
Peking Union Medical College Hospital
Organization:
Peking Union Medical College Hospital
Study Overview
Official Title:
Long-term Effect of General Anesthesia Before School Age on Neurodevelopment in Children With Congenital Scoliosis
Status:
RECRUITING
Status Verified Date:
2024-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
In the past a large number of animal studies have suggested that anesthesia exposure has potential neurotoxic effects resulting in persistent cognitive and behavioral deficits At present there is still a lack of sufficient clinical research evidence to prove whether anesthesia exposure has long-term effects on neurodevelopment The existing clinical research data suggests that a single short-time anesthesia exposure in young children does not affect long-term neurodevelopmental outcomes Early onset scoliosis including congenital scoliosis is a type of scoliosis deformity that occurs before the age of 10 Posterior scoliosis correction surgery is one of the common treatment There is currently no research indicating the impact of early single or multiple long-duration anesthesia exposure on the neurological development of children with congenital scoliosis The aim of this study is to determine the long-term effect of general anesthesia exposure on neurocognitive function and behavior in children with congenital scoliosis in order to provide reference for related clinical work
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None