Ignite Creation Date:
2024-05-06 @ 8:17 PM
Last Modification Date:
2024-10-26 @ 3:24 PM
Study NCT ID:
NCT06328673
Status:
RECRUITING
Last Update Posted:
2024-03-28
First Post:
2024-03-05
Brief Title:
A Study of DM919 Alone and in Combination With Pembrolizumab in Advanced Solid Tumors
Sponsor:
D2M Biotherapeutics Inc
Organization:
D2M Biotherapeutics Inc
Study Overview
Official Title:
A First-in-Human Open-label Phase 1a 1b Dose Escalation and Expansion Cohort Study of DM919 a Novel Anti-MICAB Antibody as Monotherapy and in Combination With Pembrolizumab in Subjects With Advanced Solid Tumors
Status:
RECRUITING
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The goal of this clinical trial is to define a safe and effective dose of DM919 for participants with solid tumors
The main questions it aims to answer are
What is the safe and effective dose of DM919 when used alone or in combination with pembrolizumab What cancers can be treated effectively with DM919 alone or in combination with pembrolizumab
Participants will be asked to attend clinic and be given a intravenous infusion of DM919 or DM-919 in combination with pembrolizumab They will have blood tests and other assessments to measure whether DM-919 will have the effect on tumors
The main questions it aims to answer are
What is the safe and effective dose of DM919 when used alone or in combination with pembrolizumab What cancers can be treated effectively with DM919 alone or in combination with pembrolizumab
Participants will be asked to attend clinic and be given a intravenous infusion of DM919 or DM-919 in combination with pembrolizumab They will have blood tests and other assessments to measure whether DM-919 will have the effect on tumors
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
True
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None