Ignite Creation Date:
2024-05-06 @ 8:17 PM
Last Modification Date:
2024-10-26 @ 3:24 PM
Study NCT ID:
NCT06326879
Status:
RECRUITING
Last Update Posted:
2024-03-25
First Post:
2024-03-18
Brief Title:
A Comparative Study Between Early Onset Colorectal Cancer and Late Onset Colorectal Cancer Patients
Sponsor:
Istituto Clinico Humanitas
Organization:
Istituto Clinico Humanitas
Study Overview
Official Title:
Early-Onset Colorectal Cancer Versus Late-Onset Colorectal Cancer a Prospective Observational Cohort Study to Explore the Clinical Sociodemographic Genetic and Molecular Characteristics Associated With Adverse Oncological Outcomes
Status:
RECRUITING
Status Verified Date:
2024-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
EOrOS
Brief Summary:
This study aims to investigate the clinical socioeconomic behavioral genetic and molecular factors characterizing Early Onset Colorectal Cancer EOCRC patients compared with Late Onset Colorectal Cancer LOCRC patients
Detailed Description:
Early Onset Colorectal Cancer EOCRC defined as a Colorectal Cancer CRC arising before the age of 50 is increasing and displays more aggressive features compared with Late Onset Colorectal Cancer LOCRC with a diagnosis after the age of 50 EOCRC patients have indeed a higher incidence rate of CRC recurrence after surgery compared with LOCRC even at early CRC stages stage I or II The reasons underlying the more aggressive patterns are almost unknown but may span and can be represented by a combination of socioeconomic factors including low economic income and access to screening programs diagnosis or therapy behavioral and lifestyle factors including diet sedentary behaviors or increased stress and anxiety and molecular or genetic factors
The aim of this study is to prospectively validate our previous retrospective findings demonstrating a higher incidence rate of CRC recurrence in early stage EOCRC and explore the possible association between lifestyle dietary socioeconomics molecular and genetic factors and postoperative CRC survival
The aim of this study is to prospectively validate our previous retrospective findings demonstrating a higher incidence rate of CRC recurrence in early stage EOCRC and explore the possible association between lifestyle dietary socioeconomics molecular and genetic factors and postoperative CRC survival
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None