Ignite Creation Date:
2024-05-06 @ 8:17 PM
Last Modification Date:
2024-10-26 @ 3:24 PM
Study NCT ID:
NCT06326073
Status:
COMPLETED
Last Update Posted:
2024-03-22
First Post:
2024-03-16
Brief Title:
Interaction Between Smoking GCF Periostin IL17A IL17E and Non-surgical Periodontal Therapy
Sponsor:
Ondokuz Mayıs University
Organization:
Ondokuz Mayıs University
Study Overview
Official Title:
Evaluation of the GCF Periostin IL-17A and IL-17E Levels of Smoking and Non-smoking Periodontitis Patients Received Periodontal Treatment Short-term Follow-up Study
Status:
COMPLETED
Status Verified Date:
2024-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
It was aimed to evaluate the changes in the levels of Periostin IL-17A and IL-17E cytokines in the gingival crevicular fluid GCF of periodontitis patients which non-surgical Phase I periodontal treatment applied to and their interactions with smoking The study included systemic healthy smokersSPn11 and non-smokersPn11 with periodontitis smokers SSn11 and non-smokersSn11 with periodontal healthy individuals Phase I periodontal treatment was applied to the groups with periodontitis Before treatment day 0 clinical measurements evaluating periodontal status were recorded and GCF samples were collected GCF samples were collected from the same tooth regions on the 15th and 30th days after treatment and clinical measurements were repeated GCF Periostin IL-17A and IL-17E levels were determined by ELISA method All data were evaluated statistically
Detailed Description:
The SH and H groups patients were instructed to visit for routine controls without receiving any periodontal treatment However after the GCF sampling patients in the SP and P groups received Non-surgical periodontal treatmentNSPT included detailed oral hygiene instruction and reinforcement in conjunction with scaling and root planning as a full mouth debridement protocol in a single session They were instructed to refrain from using any chemicals including mouthwash to remove plaque
The periodontitis patients received a follow-up call on the 15th and 30th days following treatment The GCF sampling procedure was first repeated on the teeth from which a previous GCF sample had been taken Then values for the clinical examination parameters PI GI BOP PD and CAL were once again measured and recorded Daily plaque care efficacy or deficiency was checked andor reinforced at every recall All these procedures were performed by a single investigator
The periodontitis patients received a follow-up call on the 15th and 30th days following treatment The GCF sampling procedure was first repeated on the teeth from which a previous GCF sample had been taken Then values for the clinical examination parameters PI GI BOP PD and CAL were once again measured and recorded Daily plaque care efficacy or deficiency was checked andor reinforced at every recall All these procedures were performed by a single investigator
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None