Ignite Creation Date:
2024-05-06 @ 8:18 PM
Last Modification Date:
2024-10-26 @ 3:24 PM
Study NCT ID:
NCT06328322
Status:
RECRUITING
Last Update Posted:
2024-03-25
First Post:
2024-03-18
Brief Title:
Study of Percutaneous Coronary Intervention in Left Main Coronary Artery Disease in Patients With Acute Coronary Syndrome at Sohag University Hospitals
Sponsor:
Sohag University
Organization:
Sohag University
Study Overview
Official Title:
Study of Percutaneous Coronary Intervention in Left Main Coronary Artery Disease in Patients With Acute Coronary Syndrome at Sohag University Hospitals
Status:
RECRUITING
Status Verified Date:
2024-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Acute coronary syndromes ACS encompass a spectrum of cardiovascular disorders characterized by the sudden onset of myocardial ischemia They are primarily caused by atherosclerotic plaque rupture or erosion leading to partial or complete occlusion of the coronary arteries Among the various coronary arteries affected left main coronary artery disease LMCAD is of particular concern due to its high anatomical significance and potential for adverse outcomes
The left main coronary artery LMCA is responsible for supplying a substantial portion of the left ventricular myocardium including the interventricular septum and the anterior and lateral walls Any obstruction or compromise in blood flow within this critical artery can have severe consequences including myocardial infarction heart failure or even sudden cardiac death The management of LMCAD associated with ACS represents a significant clinical challenge necessitating prompt and optimal treatment strategies
Among the various coronary arteries affected by atherosclerosis left main coronary artery disease LMCAD holds particular clinical significance due to its anatomical location and the vital role it plays in supplying a substantial portion of the left ventricular myocardium The left main coronary artery LMCA typically bifurcates into the left anterior descending artery LAD and the left circumflex artery LCX which together provide blood supply to the majority of the left ventricle including the interventricular septum and the anterior and lateral walls
The selection of an appropriate treatment strategy for LMCAD associated with ACS is a complex decision that requires careful consideration of multiple factors including patient characteristics coronary anatomy severity of ischemia and procedural expertise The emergence of several clinical trials and observational studies exploring the efficacy and safety of different revascularization strategies has further complicated the decision-making process
The left main coronary artery LMCA is responsible for supplying a substantial portion of the left ventricular myocardium including the interventricular septum and the anterior and lateral walls Any obstruction or compromise in blood flow within this critical artery can have severe consequences including myocardial infarction heart failure or even sudden cardiac death The management of LMCAD associated with ACS represents a significant clinical challenge necessitating prompt and optimal treatment strategies
Among the various coronary arteries affected by atherosclerosis left main coronary artery disease LMCAD holds particular clinical significance due to its anatomical location and the vital role it plays in supplying a substantial portion of the left ventricular myocardium The left main coronary artery LMCA typically bifurcates into the left anterior descending artery LAD and the left circumflex artery LCX which together provide blood supply to the majority of the left ventricle including the interventricular septum and the anterior and lateral walls
The selection of an appropriate treatment strategy for LMCAD associated with ACS is a complex decision that requires careful consideration of multiple factors including patient characteristics coronary anatomy severity of ischemia and procedural expertise The emergence of several clinical trials and observational studies exploring the efficacy and safety of different revascularization strategies has further complicated the decision-making process
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None