Ignite Creation Date:
2024-05-06 @ 8:18 PM
Last Modification Date:
2024-10-26 @ 3:24 PM
Study NCT ID:
NCT06324136
Status:
RECRUITING
Last Update Posted:
2024-03-21
First Post:
2024-03-01
Brief Title:
Validation Implementation and Cost-analysis of a Strategy for Personalized Diagnosis of Rare Kidney Diseases
Sponsor:
Meyer Childrens Hospital IRCCS
Organization:
Meyer Childrens Hospital IRCCS
Study Overview
Official Title:
Validation Implementation and Cost-analysis of a Strategy for Personalized Diagnosis of Rare Kidney Diseases
Status:
RECRUITING
Status Verified Date:
2024-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Chronic kidney disease CKD affects about 10 of the world population with high morbidity and mortality Genetic kidney diseases are increasingly recognized across all age groups and represent over 20 of all the causes of CKD Accurate diagnosis allows necessary and unnecessary diagnostic procedures to be defined avoids unnecessary treatments improves prognosis prediction identifies other family members for genetic counseling and defines risks for living donor kidney transplantation The research group coordinated by the Principal Investigator has recently developed an algorithm for the genetic diagnosis in pediatric and adult patients with CKD The application of this personalized diagnostic algorithm on a local study led to a global diagnostic yield of 70 suggesting that this strategy has the potential to substantially improve the diagnostic approach to patients with rare kidney disorders The aim of this study is to validate and implement these results by extending its application in a multicentric study involving nephrology units that are referral centers for rare kidney diseases at national level
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None