Ignite Creation Date:
2024-05-06 @ 8:18 PM
Last Modification Date:
2024-10-26 @ 3:24 PM
Study NCT ID:
NCT06329284
Status:
COMPLETED
Last Update Posted:
2024-03-26
First Post:
2024-03-10
Brief Title:
Midkine Role With Deregulated Oxidative and Immune Milieu in Induction of Preeclampsia
Sponsor:
Benha University
Organization:
Benha University
Study Overview
Official Title:
Midkine Interplays With Oxidative Stress and Inflammatory Milieu to Induce Preeclampsia in Normotensive Pregnant Women
Status:
COMPLETED
Status Verified Date:
2024-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Preeclampsia PE is a hypertensive pregnancy-related disorder that endangers maternal and fetal outcomes and accounts for 9-10 of maternal mortalities with its early-onset phenotype is the most dangerous but its etiology is still not fully elucidated
Midkine MDK is a multifunctional protein that plays a unique role in the development of hypertension HTN via its proatherogenic effect and induction of overexpression of angiotensin converting enzyme Oxidative stress OS upregulates the expression of MDK and MDK induces propagation of neoangiogenesis and acts as chemotactic for neutrophils
Midkine MDK is a multifunctional protein that plays a unique role in the development of hypertension HTN via its proatherogenic effect and induction of overexpression of angiotensin converting enzyme Oxidative stress OS upregulates the expression of MDK and MDK induces propagation of neoangiogenesis and acts as chemotactic for neutrophils
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None