Ignite Creation Date:
2024-05-06 @ 8:18 PM
Last Modification Date:
2024-10-26 @ 3:25 PM
Study NCT ID:
NCT06333756
Status:
COMPLETED
Last Update Posted:
2024-03-27
First Post:
2024-03-20
Brief Title:
Effects of Muscle Strengthening and Fatigue on Activities in Cortex and Muscle
Sponsor:
National Yang Ming Chiao Tung University
Organization:
National Yang Ming Chiao Tung University
Study Overview
Official Title:
Effects of Cross Education Training on Corticocortical and Corticomuscular Functional Connectivity
Status:
COMPLETED
Status Verified Date:
2022-12
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
YM110099E
Brief Summary:
We will explored the effect of cross education training on different cortex functional connectivity cortex and muscle functional connectivity and maximal voluntary contraction
Healthy participants receive cross education training of the elbow flexor 12 repset 3sets 60MVC 180s eccentricMaximal voluntary contraction electroencephalogram and electromyogram will record during cross education tasks to determine the effects of cross education training on cortical network and muscle functional connectivity
Healthy participants receive cross education training of the elbow flexor 12 repset 3sets 60MVC 180s eccentricMaximal voluntary contraction electroencephalogram and electromyogram will record during cross education tasks to determine the effects of cross education training on cortical network and muscle functional connectivity
Detailed Description:
Cross education CE training was observed in 1894 when unilateral strength training of single limb was found to increase in strength of untrained muscle group CE has potential clinical relevance in rehabilitation for patient who have acute injuries of the limb post-surgical limb immobilization and certain neurological disorders with unilateral muscle weakness Although CE has several potential clinical application the precise physiological mechanisms underlying CE remains unknown Previous studies reported that CE may involve bilateral cortical activity in both contralateral primary motor cortex cM1 and ipsilateral primary motor cortex iM1In addition neuroimaging studies have demonstrated that bilateral supplementary motor area but CE immediate change of functional connectivity in cortical network remains unknown
The purposes of this study are to investigate the immediate effect of CE training of biceps brachii 1 Immediate change of functional connectivity in cortical network 2 Immediate change of functional connectivity in cortex and target muscle 3 Explore immediate change of corticomuscular functional connectivity on maximal voluntary contraction We hypothesize that 1 Bilateral cortical motor network that exhibit changes in functional connectivity during cross education 2 Cross education would immediately enhance functional connectivity between cortex and target muscle 3 Cross education would immediately change corticomuscular functional connectivity on maximal isometric voluntary contraction
The purposes of this study are to investigate the immediate effect of CE training of biceps brachii 1 Immediate change of functional connectivity in cortical network 2 Immediate change of functional connectivity in cortex and target muscle 3 Explore immediate change of corticomuscular functional connectivity on maximal voluntary contraction We hypothesize that 1 Bilateral cortical motor network that exhibit changes in functional connectivity during cross education 2 Cross education would immediately enhance functional connectivity between cortex and target muscle 3 Cross education would immediately change corticomuscular functional connectivity on maximal isometric voluntary contraction
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None