Ignite Creation Date:
2024-05-06 @ 8:18 PM
Last Modification Date:
2024-10-26 @ 3:25 PM
Study NCT ID:
NCT06337175
Status:
RECRUITING
Last Update Posted:
2024-03-29
First Post:
2024-03-22
Brief Title:
Predictors of Post-alteplase Hemorrhagic Transformation of Brain Infarction
Sponsor:
Kafrelsheikh University
Organization:
Kafrelsheikh University
Study Overview
Official Title:
Predictors of Post-alteplase Different Subtypes of Hemorrhagic Transformation of Brain Infarction in the Middle East
Status:
RECRUITING
Status Verified Date:
2024-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The investigators evaluated whether the characteristics of ischemic stroke patients door-to-needle time and stroke risk factors were predictive variables for different subtypes of post-alteplase hemorrhagic transformation of brain infarction
Detailed Description:
Investigators conducted a prospective cohort study between June 2021 and October 2023 They screened 1450 patients who presented with AIS and received alteplase and included 616 AIS patients who met the inclusion criteria and were diagnosed based on a thorough clinical assessment including a detailed medical history physical examination and specific brain imaging results and treated with alteplase within four and half hours of stroke onset
The investigators assessed the patients follow-up brain imaging to detect the subtypes of hemorrhagic transformation after receiving alteplase
The study consisted of two distinct groups The first group consisted of 464 patients who did not experience hemorrhagic infarction while the second group comprised 152 patients who experienced hemorrhagic infarction
The investigators evaluated whether the characteristics of ischemic stroke patients door-to-needle time and stroke risk factors were predictive variables for different subtypes of post-alteplase hemorrhagic transformation of brain infarction
The investigators assessed the patients follow-up brain imaging to detect the subtypes of hemorrhagic transformation after receiving alteplase
The study consisted of two distinct groups The first group consisted of 464 patients who did not experience hemorrhagic infarction while the second group comprised 152 patients who experienced hemorrhagic infarction
The investigators evaluated whether the characteristics of ischemic stroke patients door-to-needle time and stroke risk factors were predictive variables for different subtypes of post-alteplase hemorrhagic transformation of brain infarction
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
False
Is an FDA AA801 Violation?:
None