Ignite Creation Date:
2024-05-06 @ 8:18 PM
Last Modification Date:
2024-10-26 @ 3:25 PM
Study NCT ID:
NCT06339346
Status:
ACTIVE_NOT_RECRUITING
Last Update Posted:
2024-04-01
First Post:
2024-03-25
Brief Title:
Analysis of Histopathological Factors Predictive of Lymph Node Involvement and Management Practices in pT1 Colorectal Cancers Treated by Primary Endoscopic Resection
Sponsor:
University Hospital Brest
Organization:
University Hospital Brest
Study Overview
Official Title:
Analysis of Histopathological Factors Predictive of Lymph Node Involvement and Management Practices in pT1 Colorectal Cancers Treated by Primary Endoscopic Resection a Retrospective Population-based Study
Status:
ACTIVE_NOT_RECRUITING
Status Verified Date:
2024-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
PROMOT1
Brief Summary:
Colorectal cancers CRC extending beyond the muscularis mucosae and invading the submucosa without extending beyond it are classified as pT1
Among these a number of lesions presenting pejorative criteria notably histopathological have a significant risk of lymph node invasion and are therefore candidates for partial colectomy with lymph node dissection Tumors deemed to be at low risk of lymph node involvement can be treated by endoscopy alone
It should be noted that further surgical intervention is not without comorbid consequences and that a significant proportion of post-surgical surgical specimens are free of cancerous lesions
The aim of this study is therefore to analyze the current histopathological criteria predictive of lymph node invasion in order to more accurately select candidates for surgical management
Among these a number of lesions presenting pejorative criteria notably histopathological have a significant risk of lymph node invasion and are therefore candidates for partial colectomy with lymph node dissection Tumors deemed to be at low risk of lymph node involvement can be treated by endoscopy alone
It should be noted that further surgical intervention is not without comorbid consequences and that a significant proportion of post-surgical surgical specimens are free of cancerous lesions
The aim of this study is therefore to analyze the current histopathological criteria predictive of lymph node invasion in order to more accurately select candidates for surgical management
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None