Ignite Creation Date:
2024-05-06 @ 8:19 PM
Last Modification Date:
2024-10-26 @ 3:25 PM
Study NCT ID:
NCT06339476
Status:
COMPLETED
Last Update Posted:
2024-04-03
First Post:
2024-03-25
Brief Title:
Exploring the Complex Links Between Menstrual Irregularity and Cellular Markers
Sponsor:
Cumhuriyet University
Organization:
Cumhuriyet University
Study Overview
Official Title:
Exploring the Complex Links Between Menstrual Irregularity and Cellular Markers A Focus on the Apoptosis Marker M30 the Endothelial Function Marker Asymmetric Dimethylarginine and Malondialdehyde
Status:
COMPLETED
Status Verified Date:
2024-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
A cross-sectional study design was employed involving 56 premenopausal participants with ages ranging from 20 to 49 years Serum samples were collected during the early follicular phase and levels of some biochemicals parameters analyzed
Detailed Description:
A cross-sectional study was conducted to investigate the potential relationship between menstrual regularity and the apoptosis marker caspase-cleaved cytokeratin 18 fragment M30 Asymmetric dimethylarginine ADMA and Malondialdehyde MDA levels The investigators screened 80 participants who applied for menstrual irregularity between 2023 February and 2024 March and in addition to menstrual irregularities 24 individuals with additional gynecological conditions such as polycystic ovary syndrome PCOS and endometriosis were excluded from the study In the overall study population of 56 subjects aged 20-49 were recruited from Sivas Cumhuriyet University Faculty of Medicine Research and Practice Hospital Gynecology and Obstetrics Clinic Participants were divided into two groups irregular menstrual cycle 28 participants and regular menstrual cycle control group 28 participants While those who met the criteria for menstrual irregularity were included those with another gynecological disease PCOS endometriosis etc and additional diseases diabetes insulin resistance cancer heart disease etc were excluded from the study All participants provided written informed consent before participating in the study The study protocol was approved by the Sivas Cumhuriyet University Clinical Research Ethics Committee Chairman 2023-0206 All procedures were performed in accordance with the ethical standards laid down in the Declaration of Helsinki
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None