Ignite Creation Date:
2024-05-06 @ 8:19 PM
Last Modification Date:
2024-10-26 @ 3:25 PM
Study NCT ID:
NCT06333470
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-03-28
First Post:
2024-03-21
Brief Title:
Liwan Eye Study the Fourth Follow-up
Sponsor:
Zhongshan Ophthalmic Center Sun Yat-sen University
Organization:
Zhongshan Ophthalmic Center Sun Yat-sen University
Study Overview
Official Title:
Liwan Eye Study the Fourth Follow-up
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Primary angle-closure glaucoma PACG is one of the major causes of blindness affecting more than 20 million patients worldwide The goals of this observational cohort study are to investigate the 20-year incidence of PACG in Chinese population aged 50 years and to develop prediction models for the long-term risk of progression from primary angle-closure suspect PACS to PACG
Detailed Description:
Primary angle-closure glaucoma PACG is potentially a devastating disease responsible for half of glaucoma-related blindness worldwide especially in East Asia Primary angle-closure suspect PACS which is characterized by appositional angle closure is the earliest stage of primary angle closure diseases and can finally progress to PACG Thus identifying PACS eyes at risk of angle closure is crucial for its management However the natural history of progression from PACS to PACG and its prediction models are still limited in long-term longitudinal studies Meanwhile visual impairment poses a significant global public health burden along with the accelerating trend of aging it is imperative to further evaluate the visual impairment among the elderly population
The Liwan Eye Study was a population-based study initiated in 2003 The decision to select Liwan District for the survey was taken because of its stable older population and a socioeconomic profile representative of Guangzhou as a whole At baseline 1405 eligible subjects aged 50 years and older completed a comprehensive eye examination and a questionnaire interview regarding education income hypertension and diabetes mellitus To improve the monitoring of PACS and prevent vision loss associated with PACG the purposes of this observational cohort study are to investigate the 20-year incidence of PACG in Chinese population aged over 50 years develop prediction models that include eye characteristics demographic features ocular imaging characteristics and genetic factors for the long-term risk of progression from PACS to PACG Moreover we aim to investigate the 20-year change in visual impairment and associated factors
The Liwan Eye Study was a population-based study initiated in 2003 The decision to select Liwan District for the survey was taken because of its stable older population and a socioeconomic profile representative of Guangzhou as a whole At baseline 1405 eligible subjects aged 50 years and older completed a comprehensive eye examination and a questionnaire interview regarding education income hypertension and diabetes mellitus To improve the monitoring of PACS and prevent vision loss associated with PACG the purposes of this observational cohort study are to investigate the 20-year incidence of PACG in Chinese population aged over 50 years develop prediction models that include eye characteristics demographic features ocular imaging characteristics and genetic factors for the long-term risk of progression from PACS to PACG Moreover we aim to investigate the 20-year change in visual impairment and associated factors
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None