Ignite Creation Date:
2024-05-06 @ 8:19 PM
Last Modification Date:
2024-10-26 @ 3:25 PM
Study NCT ID:
NCT06341517
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-04-02
First Post:
2023-12-04
Brief Title:
Brain Circuitry Therapeutics for Schizophrenia
Sponsor:
Indrit Begue
Organization:
University of Geneva Switzerland
Study Overview
Official Title:
Brain Circuitry Therapeutics for Schizophrenia - A Cross-species Longitudinal Randomized Controlled Clinical Study to Treat Negative Symptoms of Schizophrenia Using Non-invasive Stimulation of the Cerebellum
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
ATHENA
Brief Summary:
This project is a double blind randomized clinical trials that examines the efficacy of cerebellar non invasive stimulation for apathy improvement in patients with schizophrenia
Detailed Description:
This double-blind RCT aims to explore the efficacy of intensiveTranscranial Magnetic Stimulation TMS in schizophrenia spectrum disorders Previous studies in various disorders suggest that intensive TMS is efficacious and safe
Participants will undergo neuronavigated intermittent theta burst TMS targeted to individual network targets at an accelerated protocol multiple sessions a day The primary goal is to determine the efficacy of this protocol in alleviating negative symptoms of schizophrenia
Additionally the study will measure the impact of accelerated TMS on a range of clinical and cognitive outcomes along with neuroimaging markers indicative of symptom response
Participants will undergo neuronavigated intermittent theta burst TMS targeted to individual network targets at an accelerated protocol multiple sessions a day The primary goal is to determine the efficacy of this protocol in alleviating negative symptoms of schizophrenia
Additionally the study will measure the impact of accelerated TMS on a range of clinical and cognitive outcomes along with neuroimaging markers indicative of symptom response
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None