Ignite Creation Date:
2024-05-06 @ 8:21 PM
Last Modification Date:
2024-10-26 @ 3:26 PM
Study NCT ID:
NCT06357494
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-04-10
First Post:
2024-04-05
Brief Title:
Assessment of Thyroid Doppler Ultrasound in Followup of Pediatric Graves Disease
Sponsor:
Assiut University
Organization:
Assiut University
Study Overview
Official Title:
Assessment of Thyroid Doppler Ultrasound in Relation to Clinical and Laboratory Parameters in Follow up of Pediatric Graves Disease
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
All cases of the study will be diagnosed as Graves by History examination laboratory FT3 FT4 TSH TRAbs X-ray on left wrist for bone age neck grey scale ultrasonography for thyroid gland size shape echotexture vascularity and nodule characters if present with TIRAD score calculation
Then Color flow doppler ultrasound will be done to asses thyroid volume number of vessels per square cm and inferior thyroid artery peak systolic velocity end diastolic velocity and resistive index Patients then will receive carbimazole antithyroid drug at dose 025-05 mgkgday PO the dose will be titrated according to thyroid function test after 4-6 weeks
Beta-adrenergic blockade will be added to all symptomatic cases Regular follow up will be done every month of first 3 months of diagnosis and then every 3 months for 2 years by clinical and thyroid function test to asses response compliance complications drug side effects remission and relapses
Doppler ultrasound will be done at 0 12 and 24 months
Then Color flow doppler ultrasound will be done to asses thyroid volume number of vessels per square cm and inferior thyroid artery peak systolic velocity end diastolic velocity and resistive index Patients then will receive carbimazole antithyroid drug at dose 025-05 mgkgday PO the dose will be titrated according to thyroid function test after 4-6 weeks
Beta-adrenergic blockade will be added to all symptomatic cases Regular follow up will be done every month of first 3 months of diagnosis and then every 3 months for 2 years by clinical and thyroid function test to asses response compliance complications drug side effects remission and relapses
Doppler ultrasound will be done at 0 12 and 24 months
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None