Ignite Creation Date:
2024-05-06 @ 8:21 PM
Last Modification Date:
2024-10-26 @ 3:26 PM
Study NCT ID:
NCT06359106
Status:
RECRUITING
Last Update Posted:
2024-07-03
First Post:
2024-03-26
Brief Title:
Effects of Different Inhaled Oxygen Concentrations on Lung Function in Older Patients After Laparoscopic Gastrointestinal Surgery Under General Anesthesia
Sponsor:
China Medical University China
Organization:
China Medical University China
Study Overview
Official Title:
Effects of Different Inhaled Oxygen Concentrations on Lung Function in Older Patients After Laparoscopic Gastrointestinal Surgery Under General Anesthesia
Status:
RECRUITING
Status Verified Date:
2024-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This was a multicenter prospective parallel-grouping randomized controlled clinical study comparing low FiO2 40 and high FiO2 80 levels in older patients undergoing laparoscopic gastrointestinal surgery
Detailed Description:
This was a multicenter prospective parallel-grouping randomized controlled clinical study comparing low FiO2 40 and high FiO2 80 levels in older patients undergoing laparoscopic gastrointestinal surgery the investigators planned to enroll 1098 subjects aged 65 years for laparoscopic gastrointestinal surgery at 19 clinical trial centers in China randomized in a 11 ratio to use two inhaled oxygen concentrations during surgery All patients will be performed via the lung-protective ventilation strategy The respiratory parameters are VT 6-8mlkg PEEP 6-8 cmh2O RR 12 and respiratory rate will be adjusted by maintaining a partial pressure of carbon dioxide at 35-45 mmHg Manual lung recruitment maneuvers will be performed after tracheal intubation and before tracheal extubation The main outcome measure was the oxygenation index on the postoperative 48h The secondary outcome measures were the 7-day postoperative pulmonary complications and 30-day mortality rates et al
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None