Ignite Creation Date:
2024-05-06 @ 8:21 PM
Last Modification Date:
2024-10-26 @ 3:26 PM
Study NCT ID:
NCT06359496
Status:
COMPLETED
Last Update Posted:
2024-04-11
First Post:
2024-04-04
Brief Title:
Split or Whole Liver Transplantation A Multicenter Retrospective Cohort Study of Patients With Benign and Malignant Liver Disease
Sponsor:
Zhejiang University
Organization:
Zhejiang University
Study Overview
Official Title:
Split or Whole Liver Transplantation A Multicenter Retrospective Cohort Study of Patients With Benign and Malignant Liver Disease
Status:
COMPLETED
Status Verified Date:
2024-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The primary objective of this study was to assess the safety and feasibility of split liver transplantationSLT for adult hepatocellular carcinoma HCC patients while comparing the prognostic disparities between adult SLT and WLT also
Liver transplantation LT is an effective treatment for end-stage liver disease As a traditional marginal donor liver the application of SLT in pediatric patients is successfulHowever its application in adult liver transplantation especially in HCC patients remains controversial
This retrospective study analyze outcomes among adults who underwent SLT and whole liver transplantation WLT at two centers from January 2018 to August 2022 A 11 propensity score matching PSM analysis was performed based on important donor and recipient variables Baseline characteristics and postoperative outcomes of the above recipients were analyzed and compared Statistical significance was determined using a two-sided p-value threshold of less than 005
Liver transplantation LT is an effective treatment for end-stage liver disease As a traditional marginal donor liver the application of SLT in pediatric patients is successfulHowever its application in adult liver transplantation especially in HCC patients remains controversial
This retrospective study analyze outcomes among adults who underwent SLT and whole liver transplantation WLT at two centers from January 2018 to August 2022 A 11 propensity score matching PSM analysis was performed based on important donor and recipient variables Baseline characteristics and postoperative outcomes of the above recipients were analyzed and compared Statistical significance was determined using a two-sided p-value threshold of less than 005
Detailed Description:
The primary objective of this study was to assess the safety and feasibility of split liver transplantationSLT for adult hepatocellular carcinoma HCC patients while comparing the prognostic disparities between adult SLT and WLT also
Liver transplantation LT is an effective treatment for end-stage liver disease As a traditional marginal donor liver the application of SLT in pediatric patients is successfulHowever its application in adult liver transplantation especially in HCC patients remains controversial
This retrospective study analyze outcomes among adults who underwent SLT and whole liver transplantation WLT at two centers from January 2018 to August 2022 A 11 propensity score matching PSM analysis was performed based on important donor and recipient variables Baseline characteristics and postoperative outcomes of the above recipients were analyzed and compared Statistical significance was determined using a two-sided p-value threshold of less than 005
Liver transplantation LT is an effective treatment for end-stage liver disease As a traditional marginal donor liver the application of SLT in pediatric patients is successfulHowever its application in adult liver transplantation especially in HCC patients remains controversial
This retrospective study analyze outcomes among adults who underwent SLT and whole liver transplantation WLT at two centers from January 2018 to August 2022 A 11 propensity score matching PSM analysis was performed based on important donor and recipient variables Baseline characteristics and postoperative outcomes of the above recipients were analyzed and compared Statistical significance was determined using a two-sided p-value threshold of less than 005
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None