Ignite Creation Date:
2024-05-06 @ 8:22 PM
Last Modification Date:
2024-10-26 @ 3:26 PM
Study NCT ID:
NCT06356649
Status:
COMPLETED
Last Update Posted:
2024-04-10
First Post:
2024-03-31
Brief Title:
Investigation of the Effects of Pressure Support Ventilation and Positive Airway Pressure Modes During Extubation
Sponsor:
Eskisehir Osmangazi University
Organization:
Eskisehir Osmangazi University
Study Overview
Official Title:
Investigation of the Effects of Pressure Support Ventilation and Positive Airway Pressure Modes on Respiratory System Complications During Extubation
Status:
COMPLETED
Status Verified Date:
2024-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Controlled ventilation is applied to patients intubated for general anesthesia Additionally positive end-expiratory pressure PEEP and pressure support are mechanical ventilation modes that have been used in general anesthesia practice for many years When the recovery-extubation phase is reached intermittent bag-mask ventilation is usually used and the patient is allowed to breathe spontaneously and is extubated when an adequate respiratory level is reached It has been shown in previous studies that the use of intermittent mask ventilation causes postoperative atelectasis Different methods have been used to prevent postoperative atelectasis In our study we aimed to observe the effect of terminating general anesthesia at the end of the operation and using PEEP and pressure-supported ventilation during the extubation phase on early complications
Detailed Description:
After informed consent was obtained from the patients monitoring was performed as we practice in routine anesthesia practice Pressure controlled ventilation PCV mode and positive end-expiratory pressure PEEP were used as the mechanical ventilation mode after intubation After the operation was completed PCV mode on the mechanical ventilator was continued until the patient was extubated Afterwards patients were extubated if they complied with verbal commands andor swallowed andor coughed in response to vocal stimuli pupils were in the midline and conjugated BIS value was 80 breathing was regular and TOF response was 90 Hemodynamic and respiratory system complications were recorded during the intraoperative recovery-extubation and postoperative periods Patients over the age of 18 with American Society of Anesthesiology physical classification ASA 1-3 who underwent laparoscopic cholecystectomy were included in the study In the preoperative period the patients demographic data and hemodynamic data and in the intraoperative period respiratory data tidal volume pressure applied during inspiration peep etc and hemodynamic data were recorded Complications recorded during recovery-extubation desaturation laryngospasm bronchospasm agitation rescue mask ventilation application airway obstruction nausea-vomiting re-intubation struggling
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None