Ignite Creation Date:
2024-05-06 @ 8:22 PM
Last Modification Date:
2024-10-26 @ 3:26 PM
Study NCT ID:
NCT06350929
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-06-26
First Post:
2024-03-28
Brief Title:
Norepinephrine in the Management of General Anesthesia-Induced Arterial Hypotension in Chronic Heart Failure Patients
Sponsor:
University Hospital Toulouse
Organization:
University Hospital Toulouse
Study Overview
Official Title:
Evaluation of Norepinephrine in the Management of General Anesthesia-Induced Arterial Hypotension in Chronic Heart Failure Patients in the Operating Room
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
NORAFLOW
Brief Summary:
Arterial hypotension is a frequent complication of general anesthesia and a significant contributor to postoperative complications It is a critical marker for the development of acute renal failure and postoperative myocardial infarction Chronic heart failure CHF patients are increasingly encountered in the operating room and their perioperative morbidity and mortality are substantial with specific management lacking precise recommendations
The main objective is to assess the impact of a diluted norepinephrine bolus on cardiac output in chronic heart failure patients experiencing arterial hypotension after anesthesia induction
The main objective is to assess the impact of a diluted norepinephrine bolus on cardiac output in chronic heart failure patients experiencing arterial hypotension after anesthesia induction
Detailed Description:
Arterial hypotension is a frequent complication of general anesthesia and a significant contributor to postoperative complications It is a critical marker for the development of acute renal failure and postoperative myocardial infarction Chronic heart failure CHF patients are increasingly encountered in the operating room and their perioperative morbidity and mortality are substantial with specific management lacking precise recommendations The potential indications for norepinephrine use are expanding due to dilution methods allowing peripheral catheter administration particularly for addressing arterial hypotension during general anesthesia induction However these indications are primarily based on common practices and the impact of norepinephrine on cardiac output in patients with chronic heart failure is poorly understood The main objective is to assess the impact of a diluted norepinephrine bolus on cardiac output in chronic heart failure patients experiencing arterial hypotension after anesthesia induction
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None