Ignite Creation Date:
2024-05-06 @ 8:23 PM
Last Modification Date:
2024-10-26 @ 3:26 PM
Study NCT ID:
NCT06365957
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-04-22
First Post:
2024-04-10
Brief Title:
Acute Effects of Exercise Combined With Ketone Ester Supplement
Sponsor:
University of Macau
Organization:
University of Macau
Study Overview
Official Title:
Acute Changes in Cardiometabolic and Neurocognitive Outcomes in Response to Exercise Combined With Ketone Ester Supplement in OverweightObese Adults
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
To examine the acute changes in cardiometabolic and neurocognitive outcomes in response to exercise combined with ketone ester supplement in overweightobese adults
Detailed Description:
The prevalence of excess body weight and associated medical burdens ie cardiometabolic and neurocognitive impairments have been rising over the past several decades globally The combination of exercise and ketone supplementation has been recently proposed as one of the solutions with potential clinical value of which the interventional effects and underlying mechanisms remain unclear The current study aims at 1 investigating the additive effects of ketone ester supplements to exercise in aspects of cardiorespiratory fitness metabolism and neurocognitive status and 2 examining how the exercise type HIIE high-intensity interval exercise vs MICE moderate-intensity continuous exercise influences the cardiometabolic and neurocognitive responses of the exercise-diet regime For each of the 30 participants six experimental trials will be performed in a randomized trial with a counterbalanced order 1 HIIE-KT condition HIIE with ketone supplements 2 MICE-KT condition MICE with ketone supplements 3 NE-KT condition non-exercise with ketone supplements 4 HIIE-PLA condition HIIE with taste-matched placebo 5 MICE-PLA condition and 6 NE-PLA condition Cardiometabolic and neurocognitive parameters will be assessed before and after 30 60 and 90 min subsequently ketone ester supplements
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None