Ignite Creation Date:
2024-05-06 @ 8:23 PM
Last Modification Date:
2024-10-26 @ 3:26 PM
Study NCT ID:
NCT06366048
Status:
ACTIVE_NOT_RECRUITING
Last Update Posted:
2024-04-18
First Post:
2024-04-10
Brief Title:
A Study on Relationship Between Resected Normal Liver Parenchymal VolumeRNLVand Post-Hepatectomy Liver Failure PHLF
Sponsor:
National Natural Science Foundation of China
Organization:
National Natural Science Foundation of China
Study Overview
Official Title:
A Model Based on Resected Normal Liver Parenchymal VolumeRNLVto Predict the Risk of Post-Hepatectomy Liver Failure PHLF
Status:
ACTIVE_NOT_RECRUITING
Status Verified Date:
2024-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
RNLV
Brief Summary:
The post-hepatotectomy liver failure PHLF is still the most worrisome complication of hepatic resection Surgeons have always been making efforts to preoperatively predict PHLF using kinds of techniques scoring systems and variables The investigators of this study tried to create an individual predictive model based on the variable resected normal parenchymal volume RNLV then assessing the performance and value of the model in clinical practice
Detailed Description:
The investigator launched a large sample-size and retrospective study enrolling more than a thousand consecutive patients diagnosed with hepatocellular carcinoma HCC and intracholangiocarcinoma ICC underwent hepatotectomy from the investigators center The primary aim of study was to identify whether there was strong correlation between RNLV and PHLF and the second aim was to further build a combination model based on RNLV and evaluate the value of predicting PHLF in clinical practice The investigators attached same importance to RNLV compared to future liver remnant especially for patients with massive tumors and multiple tumors The investigators hyperthesized that RNLV could be an indicative variable for surgical safety and help to form a diversifying method to comprehensively assess the risk of PHLF preoperatively
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None