Ignite Creation Date:
2024-05-06 @ 8:24 PM
Last Modification Date:
2024-10-26 @ 3:26 PM
Study NCT ID:
NCT06364163
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-04-15
First Post:
2024-04-06
Brief Title:
Effect of Herring Oil Concentrate on LDL Cholesterol Concentration in Adults
Sponsor:
University of Bergen
Organization:
University of Bergen
Study Overview
Official Title:
A Study on the Effect of Consuming a Herring Oil Concentrate on LDL Cholesterol Concentration in Adults With Overweight or Obesity
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
High cholesterol concentration is a major risk factor for cardiovascular disease CVD and consumption of fish has been associated with a lower CVD risk in several studies The beneficial health effects of consuming fish have traditionally been ascribed to the long-chain PUFA LC-PUFA EPA C205n-3 and DHA C226n-3 although consumption of fish oils or concentrates with high EPA and DHA contents does not affect the cholesterol concentration in humans and lowers the cholesterol concentration in rats and mice only when given in very high doses Fish oils contain a plethora of fatty acids besides EPA and DHA and in recent years increased focus has been on the long-chain MUFA LC-MUFA cetoleic acid C221n-11 Cetoleic acid is found in high amounts in oils from certain fish species such as herring which has relatively low contents of both EPA and DHA The investigators have recently summarised and meta-analysed the available literature that investigates the effects of diets containing fish oils or fish oil concentrates that have a high content of cetoleic acid but low or no content of EPA and DHA on cholesterol concentration in rodents showing that cetoleic acid-rich fish oils and concentrates prevent high cholesterol concentration
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None