Ignite Creation Date:
2024-05-06 @ 8:24 PM
Last Modification Date:
2024-10-26 @ 3:26 PM
Study NCT ID:
NCT06365138
Status:
RECRUITING
Last Update Posted:
2024-04-15
First Post:
2024-01-29
Brief Title:
Analysis of Individual Activity at the Time of Aortic Rupture in Patients With Abdominal Aortic Aneurysms
Sponsor:
University Hospital Augsburg
Organization:
University Hospital Augsburg
Study Overview
Official Title:
Analysis of Individual Activity at the Time of Aortic Rupture in Patients With Abdominal Aortic Aneurysms
Status:
RECRUITING
Status Verified Date:
2024-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
It is currently unclear what activities aneurysms are involved in at the time of rupture The aim of the study is to determine the activity performed at the time of aneurysm rupture
Detailed Description:
The scientifically proven risk factors that significantly favor the rupture of an aortic aneurysm are female gender the maximum diameter of the aortic aneurysm and the patients current smoking status
However no analysis of the occupation performed at the time of aortic rupture of an abdominal aortic aneurysm has yet been carried out
High arterial systolic blood pressure can promote aortic rupture Blood pressure peaks can occur during physical exertion for example when lifting heavy loads or during defecation
Patients with an existing intact aortic aneurysm are currently advised to avoid such behaviors as a preventive measure This includes among other things the practice of strength training or certain types of sport This can subsequently lead to a reduction in quality of life although this cannot currently be substantiated by scientific data There is also no current guideline recommendation in this regard
Furthermore the role of stress and or emotionally stressful events in connection with the occurrence of aortic ruptures has not yet been recorded in the literature There is work on this in connection with aortic dissections which postulates that an increase in emotional or psychological stress can lead to acute hypertension which can cause a previously damaged aorta to rupture A similar pathomechanism would also be conceivable for the rupture of aortic aneurysms
There are indications that in addition to gender-specific differences in the occurrence of aortic ruptures there is also a different risk of rupture based on certain pre-existing conditions dietary habits and age
However no analysis of the occupation performed at the time of aortic rupture of an abdominal aortic aneurysm has yet been carried out
High arterial systolic blood pressure can promote aortic rupture Blood pressure peaks can occur during physical exertion for example when lifting heavy loads or during defecation
Patients with an existing intact aortic aneurysm are currently advised to avoid such behaviors as a preventive measure This includes among other things the practice of strength training or certain types of sport This can subsequently lead to a reduction in quality of life although this cannot currently be substantiated by scientific data There is also no current guideline recommendation in this regard
Furthermore the role of stress and or emotionally stressful events in connection with the occurrence of aortic ruptures has not yet been recorded in the literature There is work on this in connection with aortic dissections which postulates that an increase in emotional or psychological stress can lead to acute hypertension which can cause a previously damaged aorta to rupture A similar pathomechanism would also be conceivable for the rupture of aortic aneurysms
There are indications that in addition to gender-specific differences in the occurrence of aortic ruptures there is also a different risk of rupture based on certain pre-existing conditions dietary habits and age
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None