Ignite Creation Date:
2024-05-06 @ 8:24 PM
Last Modification Date:
2024-10-26 @ 3:26 PM
Study NCT ID:
NCT06366061
Status:
RECRUITING
Last Update Posted:
2024-04-15
First Post:
2022-05-13
Brief Title:
A COMPARISON OF LEFT VENTRICULAR FUNCTION IN THE APICAL 4 CHAMBER AND SUBCOSTAL 4 CHAMBER TTE VIEWS IN THE PERIOPERATIVE SETTING
Sponsor:
Eckhard Mauermann
Organization:
University Hospital Basel Switzerland
Study Overview
Official Title:
A COMPARISON OF LEFT VENTRICULAR FUNCTION IN THE APICAL 4 CHAMBER AND SUBCOSTAL 4 CHAMBER TTE VIEWS IN THE PERIOPERATIVE SETTING A PROSPECTIVE CLINICAL TRIAL
Status:
RECRUITING
Status Verified Date:
2024-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study aims to examine the correlation and agreement of regional and global measurements of ventricular function in the apical 4 chamber and subcostal 4 chamber view Additionally we will explore limitations of the technology and explore the effect of left lateral positioning
Detailed Description:
In transthoracic echocardiography a number of measures are endorsed by current guidelines for quantifying ventricular function These include conventional mitral annular plane velocities ejection fraction and novel speckle-tracking STE technologies However these measurements are standardized to be measured in the left lateral decubitus position in the apical 4-chamber view of awake spontaneously breathing patients
In the perioperative period however attaining these measurements in the endorsed circumstances may be challenging for a number of reasons First obtaining usable AP4C images may be difficult in ventilated or post-surgical patients While the SC4C is generally obtainable visualized structures are not identical to those of the AP4C and measurement technologies such as Doppler are misaligned Secondly patient conditions eg in distress or during surgery may preclude positioning the patient in the left lateral decubitus position Finally patients may be ventilated and under anesthesia
Newer technologies - such as speckle-tracking- may partially overcome these difficulties as these technologies are considered to be relatively angle independent For quantification it would be important to know whether or not speckle-tracking based measurements in the SC4C are sufficiently close to those measured under the endorsed conditions
In the perioperative period however attaining these measurements in the endorsed circumstances may be challenging for a number of reasons First obtaining usable AP4C images may be difficult in ventilated or post-surgical patients While the SC4C is generally obtainable visualized structures are not identical to those of the AP4C and measurement technologies such as Doppler are misaligned Secondly patient conditions eg in distress or during surgery may preclude positioning the patient in the left lateral decubitus position Finally patients may be ventilated and under anesthesia
Newer technologies - such as speckle-tracking- may partially overcome these difficulties as these technologies are considered to be relatively angle independent For quantification it would be important to know whether or not speckle-tracking based measurements in the SC4C are sufficiently close to those measured under the endorsed conditions
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None