Ignite Creation Date:
2024-05-06 @ 8:24 PM
Last Modification Date:
2024-10-26 @ 3:27 PM
Study NCT ID:
NCT06376890
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-04-19
First Post:
2024-04-12
Brief Title:
Effects of Chili Pepper on Inflammation and Glycemic Control in Southern New Mexico
Sponsor:
New Mexico State University
Organization:
New Mexico State University
Study Overview
Official Title:
Effects of Chili Pepper on Inflammation and Glycemic Control in Southern New Mexico
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Diabetes is a major health epidemic facing the United States and New Mexico Currently 116 of the US population 384 million has diabetes and 380 of US adults have prediabetes It is estimated that around 70 of prediabetics will develop diabetes in their lifetime In New Mexico 48 of adults are at least prediabetic and 12 of adults in southern New Mexico adults have diabetes Moreover major health disparities challenge the southern New Mexico region Type 2 diabetes mellitus T2DM is generally linked with chronic inflammation obesity insulin resistance and ultimately insulin dependence via pancreatic β-cell failure Lessening pathological inflammation a critically important factor that contributes to diabetes can improve the disease Furthermore 898 of diabetics in the US are overweight or obese this is a major risk for prediabetes and T2DM as it causes insulin resistance and pancreatic β-cell dysfunction Weight loss in people with T2DM and prediabetes has been demonstrated to affect glycemic control and metabolic parameters significantly The purpose of this proposed study is to explore and establish the beneficial effects of 10 weeks of powdered chili pepper consumption on several parameters related to diabetes and prediabetes This research will demonstrate how powdered chili pepper consumption can improve systemic inflammation glycemic control and body composition and will provide valuable preliminary data for future funding to further examine these effects in Type 2 diabetics This research is innovative because chili peppers are an already widely accepted food in Southern New Mexico Demonstrating the beneficial improvements in diabetes-related markers using a popular food in the area may help to establish better treatments and protocols for an area that has health disparities The first aim is to establish if 10 weeks of powdered red or green chili pepper consumption can significantly improve markers of inflammation inflammatory capacity and antioxidant capacity The second aim is to establish if 10 weeks of powdered red or green chili pepper ingestion has a significant effect on resting blood glucose and insulin levels connecting peptide C-peptide levels and Homeostatic Model Assessment for Insulin Resistance HOMA-IR The third aim is to determine whether powdered chili pepper consumption for 10 weeks improves resting body composition and metabolic rate This research is innovative because chili peppers are an already widely accepted food in Southern New Mexico Demonstrating the beneficial improvements in diabetes-related markers using a popular food in the area may help to establish better treatments and protocols for an area with health disparities Overall this study will provide valuable insight and background knowledge for the use of chili peppers for the treatment of prediabetes and the prevention of diabetes progression
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None