Ignite Creation Date:
2024-05-06 @ 8:25 PM
Last Modification Date:
2024-10-26 @ 3:27 PM
Study NCT ID:
NCT06373848
Status:
ENROLLING_BY_INVITATION
Last Update Posted:
2024-05-06
First Post:
2024-04-16
Brief Title:
Comparison of Salivary Parameters in Patients Receiving CoQ10 and Vitamin E Supplementation
Sponsor:
Islamic Azad University Tehran
Organization:
Islamic Azad University Tehran
Study Overview
Official Title:
Comparison of Salivary Markers in Patients With Initial Chronic Periodontitis After Non-surgical Periodontal Treatment With CoQ10 Supplementation With Vitamin E
Status:
ENROLLING_BY_INVITATION
Status Verified Date:
2024-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Comparison of salivary markers in patients with Initial chronic periodontitis after non-surgical periodontal treatment with CoQ10 supplementation with vitamin E
Detailed Description:
This research was structured as a double-blind randomized clinical trial aimed at assessing the effectiveness of CoQ10 and Vitamin E supplements on periodontal health in patients with chronic periodontitis A total of 75 patients from the Department of Periodontics at Broujerd Dental School of the Islamic Azad University of Medical Sciences were chosen for the study Before the commencement of the trial various clinical periodontal parameters such as plaque index bleeding on probing gingival index probing depth and clinical attachment level were measured in six different areas of the tooth surface Subsequently scaling and root planning were carried out and oral hygiene practices were enhanced for all participants The participants were then randomly divided into three groups Group A received 30 mg of CoQ10 Group B was provided with 400 mg of Vitamin E supplements daily and Group C did not receive any medication After two months the clinical periodontal parameters were reevaluated Furthermore to compare the total antioxidant capacity in saliva before and after the administration of these supplements as well as in patients who did not receive any medication 2 ml of non-stimulated saliva was collected from each participant at the beginning and end of the study for analysis using UV-spectrophotometric methods The selection criteria for eligible participants in this study were also clearly defined
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None