Ignite Creation Date:
2024-05-06 @ 8:26 PM
Last Modification Date:
2024-10-26 @ 3:28 PM
Study NCT ID:
NCT06388148
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-05-28
First Post:
2024-04-21
Brief Title:
Endovascular Treatment for eXtra-Large Ischemic Stroke
Sponsor:
Zhongming Qiu
Organization:
Xinqiao Hospital of Chongqing
Study Overview
Official Title:
Efficacy and Safety of Endovascular Thrombectomy Plus Medical Management Versus Medical Management Alone in Acute Ischemic Stroke Patients With Large Vessel Occlusion and Extra-Large Infarct Core A Multicenter Randomized Controlled Trial
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
XL STROKE-2
Brief Summary:
The role of endovascular thrombectomy in patients with extra-large ischemic burden is still unclear The XL STROKE-2 randomized trial is aiming to investigate the efficacy and safety of mechanical thrombectomy in acute extra-large ischemic stroke patients with large vessel occlusion
Detailed Description:
Several randomized trials have shown that endovascular thrombectomy improve functional outcomes in acute ischemic stroke patients with large vessel occlusion Recently six randomized controlled trials demonstrated the efficacy and safety of endovascular thrombectomy for large infarct patients defined as Alberta Stroke Program Early Computed Tomography Score ASPECTS 3 or infarct core 100ml Patients with extra-large infarct core volume greater than 100 mL ASPECTS score of 0 to 2 accounted for a small proportion of these trials Therefore the role of endovascular thrombectomy in patients with extra-large ischemic burden is still unclear That is to say exactly where the lower limit of endovascular thrombectomy is unknown The XL STROKE-2 randomized trial is aiming to investigate the efficacy and safety of mechanical thrombectomy in acute extra-large ischemic stroke patients with large vessel occlusion
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None