Ignite Creation Date:
2024-05-06 @ 8:27 PM
Last Modification Date:
2024-10-26 @ 3:28 PM
Study NCT ID:
NCT06386120
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-04-26
First Post:
2024-04-24
Brief Title:
Respiratory Function Monitoring of Mechanical Ventilation in Patients With Chest Blunt Injury
Sponsor:
Peking University Peoples Hospital
Organization:
Peking University Peoples Hospital
Study Overview
Official Title:
Respiratory Function Monitoring of Patients With Chest Blunt Injury With Mechanical Ventilation
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The goal of this observational study is to learn about EIT in observing the application of lung protective ventilation strategies in patients with pulmonary contusion particularly the impact on pulmonary ventilation blood flow ratio oxygen and condition The main question it aims to answer is
Can lung protective ventilation strategies improve respiratory function in patients with severe chest contusion We will collect clinical data of participants who already taking lung protective ventilation strategies as part of their regular medical care
Can lung protective ventilation strategies improve respiratory function in patients with severe chest contusion We will collect clinical data of participants who already taking lung protective ventilation strategies as part of their regular medical care
Detailed Description:
Trauma is the leading cause of death among middle-aged and young people in China with over 25 of patients dying from chest trauma The incidence of pulmonary contusion in severe chest trauma is over 70 and it is an important cause of respiratory failure and even death in patients The occurrence of pulmonary contusion and respiratory failure in patients with chest contusion is a dynamic process and Regional inhomogeneities of the damaged lung should be taken into consideration to develop improved ventilation strategies Currently there is no ideal monitoring method to evaluate the severity of injury and guide the ventilation strategies Electrical impedance tomography EIT is a non-invasive radiation-free imaging technique It measures regional lung ventilation and aeration distribution by means of changes in electrical potentials at the skin surface of the chest wall during breathing cycles which has been proven to have good practicality in patients with non-invasive ARDS and pulmonary embolism In this study we aim to characterize the physiologic effects of positive end expiratory pressure PEEP on key mechanisms of regional lung protection namely recruitment reduced atelectrauma and improved ventilation-perfusion matching by CT scan and EIT
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None