Ignite Creation Date:
2024-05-06 @ 8:27 PM
Last Modification Date:
2024-10-26 @ 3:28 PM
Study NCT ID:
NCT06387901
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-04-29
First Post:
2024-04-09
Brief Title:
Investigating Paclitaxel Toxicity in Breast Cancer The Roles of Physical Activity and Body Composition
Sponsor:
Universitair Ziekenhuis Brussel
Organization:
Universitair Ziekenhuis Brussel
Study Overview
Official Title:
Dose-limiting Toxicities of Paclitaxel in Breast Cancer Patients Studying Interactions Between Pharmacokinetics Physical Activity and Body Composition an Observational Pilot Study
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
PABTOX
Brief Summary:
This study looks into how a common breast cancer treatment paclitaxel can sometimes cause severe side effects that make it hard for patients to continue treatment These side effects can significantly affect a patients quality of life and even impact their recovery and overall health costs Whats interesting about this research is that it considers how a patients lifestyle specifically their physical activity levels and body makeup like how much muscle and fat they have might influence these side effects
The researchers are doing a detailed study with 40 women receiving paclitaxel treatment tracking how the drug is processed in their bodies and how their body composition and physical activity might play a role in the side effects they experience They are using a special method to monitor drug levels in the blood and are also keeping tabs on the patients health and physical activity through questionnaires and modern tracking devices
The goal here is twofold first to better understand why these side effects happen to some people and not others and second to develop a model that can predict who might be at higher risk for these side effects based on their body composition lifestyle and how their body handles the drug This could lead to more personalized treatment plans that could help reduce the risk of severe side effects and improve the overall treatment experience for patients with breast cancer
In simpler terms this research is trying to find a way to make breast cancer treatment with paclitaxel safer and more comfortable by considering how a persons lifestyle and body type might affect their reaction to the drug This could make a big difference in helping patients complete their treatment successfully and with a better quality of life
The researchers are doing a detailed study with 40 women receiving paclitaxel treatment tracking how the drug is processed in their bodies and how their body composition and physical activity might play a role in the side effects they experience They are using a special method to monitor drug levels in the blood and are also keeping tabs on the patients health and physical activity through questionnaires and modern tracking devices
The goal here is twofold first to better understand why these side effects happen to some people and not others and second to develop a model that can predict who might be at higher risk for these side effects based on their body composition lifestyle and how their body handles the drug This could lead to more personalized treatment plans that could help reduce the risk of severe side effects and improve the overall treatment experience for patients with breast cancer
In simpler terms this research is trying to find a way to make breast cancer treatment with paclitaxel safer and more comfortable by considering how a persons lifestyle and body type might affect their reaction to the drug This could make a big difference in helping patients complete their treatment successfully and with a better quality of life
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None