Ignite Creation Date:
2024-05-06 @ 8:27 PM
Last Modification Date:
2024-10-26 @ 3:28 PM
Study NCT ID:
NCT06397430
Status:
COMPLETED
Last Update Posted:
2024-05-02
First Post:
2024-04-11
Brief Title:
Nutritional Support for Patients Operated for Malignant Tumors in HPD Zone
Sponsor:
Karaganda Medical University
Organization:
Karaganda Medical University
Study Overview
Official Title:
Nutritional Support for Patients Operated on for Malignant Tumors of the Hepatico-pancreato-duodenal HPD Zone in the Early Postoperative Period
Status:
COMPLETED
Status Verified Date:
2024-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
A comprehensive comparative analysis of the effectiveness of isolated enteral isolated parenteral and mixed type of nutritional support in the early postoperative period in patients after operations performed on the malignant neoplasms of hepatico-pancreatico-duodenal zone
Detailed Description:
A prospective longitudinal parallel study and retrospective analysis of the results of treatment of 91 patients with malignant tumors of the hepatico-pancreato-duodenal zone who underwent the following operations
1 resection of various segments of the liver
2 hemihepatectomy
3 transhepatic drainage of the right and left hepatic duct
4 bypass gastroenteroanastomosis or cholecystenteroanastomosis with interintestinal enteroenteroanastomosis according to Brown
5 gastro-pancreato-duodenal resection
6 corpore-caudal resection of the pancreas with splenectomy
The first group n31 included patients who received enteral nutrition EN after surgery The second group n30 included patients who received parenteral nutrition PN and the third group n30 who received mixed nutrition MN as a variation of the partial parenteral nutrition technique in the early postoperative period
Some nutritional status indicators available for determination at the Oncology Clinic were assessed - body mass index weight measurements were carried out before surgery on the 5th 10th and 15th days basal metabolic rate calculated using the Harris-Benedict equation based on anthropometric data of the patient gender age weight and height laboratory parameters blood hemoglobin lymphocytes total protein serum albumin serum transferrin total bilirubin and direct alanine aminotransferase ALT aspartate aminotransferase AST which are related to the traditional method for assessing nutritional status
1 resection of various segments of the liver
2 hemihepatectomy
3 transhepatic drainage of the right and left hepatic duct
4 bypass gastroenteroanastomosis or cholecystenteroanastomosis with interintestinal enteroenteroanastomosis according to Brown
5 gastro-pancreato-duodenal resection
6 corpore-caudal resection of the pancreas with splenectomy
The first group n31 included patients who received enteral nutrition EN after surgery The second group n30 included patients who received parenteral nutrition PN and the third group n30 who received mixed nutrition MN as a variation of the partial parenteral nutrition technique in the early postoperative period
Some nutritional status indicators available for determination at the Oncology Clinic were assessed - body mass index weight measurements were carried out before surgery on the 5th 10th and 15th days basal metabolic rate calculated using the Harris-Benedict equation based on anthropometric data of the patient gender age weight and height laboratory parameters blood hemoglobin lymphocytes total protein serum albumin serum transferrin total bilirubin and direct alanine aminotransferase ALT aspartate aminotransferase AST which are related to the traditional method for assessing nutritional status
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None