Ignite Creation Date:
2024-05-06 @ 8:28 PM
Last Modification Date:
2024-10-26 @ 3:28 PM
Study NCT ID:
NCT06397378
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-05-02
First Post:
2024-04-12
Brief Title:
Engaging College Students in Developing and Testing a Video-based Intervention for HPV Vaccination Promotion
Sponsor:
Michigan State University
Organization:
Michigan State University
Study Overview
Official Title:
Development and Pilot Testing a Video-based Intervention to Promote HPV Vaccination Among College Students
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
HPV videos
Brief Summary:
HPV vaccines offer hope against HPV-associated cancers for males and females however the rate of vaccination has not reached projected public health goals This study will engage key stakeholders in the research process to co-design and pilot testing a video-based intervention addressing low HPV vaccination rates among college students The intervention and its approach have the potential to reduce health disparities in HPV-associated cancers in young adults via low-cost technology and timely intervention
Detailed Description:
Human papillomavirus HPV infection is the most common sexually transmitted infection in the United States US and a significant public health issue as almost all sexually active individuals contract it at some point in their lives Approximately 79 million Americans are infected with HPV most in their late teens or early 20s HPV has been found to be associated with cancers for females eg cervical cancer and males eg penile cancer The high morbidity mortality and economic burden attributed to cancer-causing HPV call for researchers to address this public health concern through vigorous prevention efforts including HPV vaccination
HPV-associated cancers could be prevented through vaccination HPV vaccination is recommended for individuals aged 9-26 years Economic models have shown that HPV vaccination of adolescents and young adults is cost effective however HPV vaccination rates are falling dramatically short of the 80 Healthy People 2030 target recommendation Young adults such as college students are at higher risk for HPV infection but a significant portion of them is not yet vaccinated against HPV
Empirical evidence suggests that a lack of awareness and knowledge about HPV and the vaccine the inconvenience of getting the vaccine and concern about side effects are main barriers for college students Current interventions developed to increase HPV vaccination rates are primarily focusing on adolescents as recipients In the limited interventions developed to address low HPV vaccination rates among college students most of them only included female college students In one online RCT study that young adults aged 18-26 were randomized into intervention group YouTube videos reported significantly higher vaccination intention compared to comparison group educational pamphlet however the vaccination status was not assessed College students have advocated for educational videos featuring healthcare providers and peers and sharing videos on YouTube and Instagram
To our knowledge this study is the first one of a few video-based interventions co-designed with the main stakeholder-college students to address the low HPV vaccination rates in this at-risk population This novel intervention is brief portable tailored to college students and feasible to fit the intervention into college student39s busy schedules
The investigators will develop a video-based intervention and conduct a pilot randomized trial comparing this intervention to an HPV Fact Sheet developed by CDC The investigators will target college students aged 18-26 because of their higher risk of contracting HPV infection and low vaccination rates Aim 1 Develop a developmentally and culturally congruent video-based intervention for college students aged 18-26 The investigators will recruit and form a student advisory board SAB consisting of 8-10 college students aged 18-26 to assist with developing four brief HPV education videos each 2-3 mins long two will be revised from Co-Is prior research The advisory board will provide input on the study recruitment plan assessments and be involved in data interpretation and dissemination processes Aim 2 Conduct a pilot randomized controlled trial RCT to examine the feasibility participation rate retention intervention fidelity acceptability satisfaction and preliminary efficacy of the intervention to promote HPV vaccination among 80 college students aged 18-26
Once consented participants will receive assessments at baseline T0 using the web-based data collection tool Qualtrics before being assigned to one of the two study arms Participants will be invited to fill out Time 1 T1 assessment immediately after the intervention video vs Fact Sheet and Time 2 T2 assessment 2 months after completion of the intervention The interventions video and CDC Fact Sheet and T0-T2 assessments will be administered online A resource kit including available resources to obtain vaccines will be provided to all participants after T2 assessment The investigators will also provide the video-based intervention to the students in the comparison arm after T2 assessment should they be interested Videos will be sent out after participants complete T0 One video will be sent out every 3 days and the intervention 4 videos in total will be completed in 2-week via emails Participants in the intervention group can watch the videos at their leisure
Feasibility will be assessed by response rate percentage of eligible individuals agreeing to participate retention proportion retained through follow-up and complete T0-T2 assessments intervention fidelity of participants watch all stories Acceptability will be assessed via two Likert-type satisfaction questions Based on our prior research the investigators will use the following benchmarks to determine study feasibility as 80 response rate 80 retention rate 80 intervention fidelity and acceptability by a mean satisfaction score 40 Preliminary efficacy will be determined by the of participants completing the 1st HPV vaccine does within 2 months of completing the intervention
HPV-associated cancers could be prevented through vaccination HPV vaccination is recommended for individuals aged 9-26 years Economic models have shown that HPV vaccination of adolescents and young adults is cost effective however HPV vaccination rates are falling dramatically short of the 80 Healthy People 2030 target recommendation Young adults such as college students are at higher risk for HPV infection but a significant portion of them is not yet vaccinated against HPV
Empirical evidence suggests that a lack of awareness and knowledge about HPV and the vaccine the inconvenience of getting the vaccine and concern about side effects are main barriers for college students Current interventions developed to increase HPV vaccination rates are primarily focusing on adolescents as recipients In the limited interventions developed to address low HPV vaccination rates among college students most of them only included female college students In one online RCT study that young adults aged 18-26 were randomized into intervention group YouTube videos reported significantly higher vaccination intention compared to comparison group educational pamphlet however the vaccination status was not assessed College students have advocated for educational videos featuring healthcare providers and peers and sharing videos on YouTube and Instagram
To our knowledge this study is the first one of a few video-based interventions co-designed with the main stakeholder-college students to address the low HPV vaccination rates in this at-risk population This novel intervention is brief portable tailored to college students and feasible to fit the intervention into college student39s busy schedules
The investigators will develop a video-based intervention and conduct a pilot randomized trial comparing this intervention to an HPV Fact Sheet developed by CDC The investigators will target college students aged 18-26 because of their higher risk of contracting HPV infection and low vaccination rates Aim 1 Develop a developmentally and culturally congruent video-based intervention for college students aged 18-26 The investigators will recruit and form a student advisory board SAB consisting of 8-10 college students aged 18-26 to assist with developing four brief HPV education videos each 2-3 mins long two will be revised from Co-Is prior research The advisory board will provide input on the study recruitment plan assessments and be involved in data interpretation and dissemination processes Aim 2 Conduct a pilot randomized controlled trial RCT to examine the feasibility participation rate retention intervention fidelity acceptability satisfaction and preliminary efficacy of the intervention to promote HPV vaccination among 80 college students aged 18-26
Once consented participants will receive assessments at baseline T0 using the web-based data collection tool Qualtrics before being assigned to one of the two study arms Participants will be invited to fill out Time 1 T1 assessment immediately after the intervention video vs Fact Sheet and Time 2 T2 assessment 2 months after completion of the intervention The interventions video and CDC Fact Sheet and T0-T2 assessments will be administered online A resource kit including available resources to obtain vaccines will be provided to all participants after T2 assessment The investigators will also provide the video-based intervention to the students in the comparison arm after T2 assessment should they be interested Videos will be sent out after participants complete T0 One video will be sent out every 3 days and the intervention 4 videos in total will be completed in 2-week via emails Participants in the intervention group can watch the videos at their leisure
Feasibility will be assessed by response rate percentage of eligible individuals agreeing to participate retention proportion retained through follow-up and complete T0-T2 assessments intervention fidelity of participants watch all stories Acceptability will be assessed via two Likert-type satisfaction questions Based on our prior research the investigators will use the following benchmarks to determine study feasibility as 80 response rate 80 retention rate 80 intervention fidelity and acceptability by a mean satisfaction score 40 Preliminary efficacy will be determined by the of participants completing the 1st HPV vaccine does within 2 months of completing the intervention
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| PD66847 | OTHER | Michigan State University Trifecta Initiative Fubd | None |