Ignite Creation Date:
2024-05-06 @ 8:28 PM
Last Modification Date:
2024-10-26 @ 3:28 PM
Study NCT ID:
NCT06397677
Status:
RECRUITING
Last Update Posted:
2024-05-03
First Post:
2023-12-01
Brief Title:
Defining the Molecular and Radiologic Phenotype of Progressive RA Interstitial Lung Disease
Sponsor:
University of Colorado Denver
Organization:
University of Colorado Denver
Study Overview
Official Title:
Defining the Molecular and Radiologic Phenotype of Progressive RA Interstitial Lung Disease MOUNTAIN
Status:
RECRUITING
Status Verified Date:
2024-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
MOUNTAIN
Brief Summary:
A study to identify patients with Rheumatoid Arthritis - Associated Interstitial Lung Disease RA-ILD that are at the highest risk for progression
The goal of the investigators is to recruit a group of patients with RA-ILD and collect information to help us understand more about disease progression The investigators will do this using a combination of clinical radiologic and biologic features
The goal of the investigators is to recruit a group of patients with RA-ILD and collect information to help us understand more about disease progression The investigators will do this using a combination of clinical radiologic and biologic features
Detailed Description:
The central hypothesis is that novel quantitative imaging and specific blood markers will be associated with progressive RA-ILD The hypothesis will be tested through collection and analysis of peripheral blood in addition to the analysis of HRCT high-resolution computed tomography scans performed as standard of care clinical on research subjects
Procedures performed
Baseline Year 0 Blood sample buccal cheek swab questionnaires and if performed clinically - Pulmonary Function tests 6 Minute Walk Test and HRCT scan of lungs
Every 4 months at clinic visit Blood sample questionnaires
Year 1 and Year 2 Follow-ups Blood sample buccal cheek swab questionnaires and if performed clinically - Pulmonary Function tests 6 Minute Walk Test and HRCT scan of lungs
Procedures performed
Baseline Year 0 Blood sample buccal cheek swab questionnaires and if performed clinically - Pulmonary Function tests 6 Minute Walk Test and HRCT scan of lungs
Every 4 months at clinic visit Blood sample questionnaires
Year 1 and Year 2 Follow-ups Blood sample buccal cheek swab questionnaires and if performed clinically - Pulmonary Function tests 6 Minute Walk Test and HRCT scan of lungs
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 1R01HL168126-01 | NIH | None | httpsreporternihgovquickSearch1R01HL168126-01 |