Ignite Creation Date:
2024-05-06 @ 8:29 PM
Last Modification Date:
2024-10-26 @ 3:28 PM
Study NCT ID:
NCT06395454
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-06-03
First Post:
2024-04-24
Brief Title:
Usage of Procalcitonin to Reduce Antibiotics Duration in VAP in Neurosurgical ICU
Sponsor:
Universiti Sains Malaysia
Organization:
Universiti Sains Malaysia
Study Overview
Official Title:
Procalcitonin as a Sepsis Biomarker in Guiding Antibiotics Treatment Duration in Ventilator Associated Pneumonia in Neuro-ICU A Randomised Controlled Trial
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Using Procalcitonin Tests to reduce antibiotics duration in Neurosurgical patients with Ventilated Associated Pneumonia
Detailed Description:
Patients who are more than 18 years old who are admitted to Neurosurgical ICU will be recruited 48hours after ventilation if matches criteria for ventilator associated pneumonia Patients will be randomised into 2 groups first group will be procalcitonin guided in addition to conventionally guided sepsis assessment TWC CRP body temperature second group is only conventionally guided sepsis assessment in procalcitonin guided group blood sample will be taken on Day 1 of recruitment and day 5 On day 5 the procalcitonin level will be compared to recommendations in PRORATA trial If procalcitonin level is below the level to withhold antibiotics recommendation will be made to the primary physician to off the antibiotics Another Procalcitonin level will be repeated on Day 7 to rule out reinfection This study aims to compare the duration of antibiotics and length of ICU stay among the 2 groups
This study will fill up the gap among the lack of datas in neurosurgical patients
This study will fill up the gap among the lack of datas in neurosurgical patients
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None