Ignite Creation Date:
2024-05-11 @ 8:30 AM
Last Modification Date:
2024-10-26 @ 3:29 PM
Study NCT ID:
NCT06405048
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-05-08
First Post:
2024-04-26
Brief Title:
Impact of a Mock-up Fact-checking Extension on HPV Vaccine Misinformation A Survey Experiment
Sponsor:
Fudan University
Organization:
Fudan University
Study Overview
Official Title:
Evaluating the Feasibility and Effectiveness of a Mock-up Fact-checking Extension to Improve Ability to Debunk HPV Vaccine Misinformation Among Parents of Middle School Girls A Survey Experiment
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The primary objective of this survey experiment study is to measure the impact of a mock-up Chinese fact-checking extension on the ability to dispel HPV and HPV vaccine-related misinformation among parents of middle school girls in China
Detailed Description:
This survey experiment study aims to assess the feasibility and effectiveness of a mock-up Chinese fact-checking extension on improving the ability to identify HPV and HPV vaccine-related misinformation among parents of middle school girls in three economically diverse regions of China This includes Shanghai megacity an urban city in Anhui Province and rural counties in Anhui Province The participants will be parents of middle school girls who have not yet received the HPV vaccine This experiment will randomly assign the participants into intervention or control group Participants in the intervention group will use a mock-up Chinese fact-checking extension whereas those in control group will not
The sample size for this study was determined based on the two primary outcomes knowledge of the HPV vaccine and the ability to dispel misinformation A review of the existing literature suggests that the intention or confidence among Chinese parents to vaccinate their children with the HPV vaccine as well as their knowledge about the vaccine and capability to counteract misinformation typically ranges from 50 to 70 We assumed a baseline rate of 60 for both vaccine knowledge and misinformation discernment It is anticipated that exposure to educational interventions will increase these rates by 10 elevating them to 70 Using a significance level of 005 and a statistical power of 90 the required sample size was calculated to be a minimum of 473 participants per group To accommodate potential variability and to strengthen the robustness of the study 500 participants will be recruited for each group maintaining a 11 ratio This approach results in a total sample size of 1000 participants Such a sample size ensures that the study is sufficiently powered to detect a significant change in the outcomes of interest
In this study 11 mobile Weibo post screenshots were created covering a range of topics including infertility safety vaccine ingredients high-risk cervical cancer types regular check-ups transmission routes and others
The participants in both groups will complete a questionnaire consisting of six phases
1 Phase 1 Baseline Assessment Participants in both the intervention and control groups will complete a questionnaire covering a basic demographic information b HPV vaccine knowledge c HPV vaccine awareness and confidence and d vaccination intentions
2 Phase 2 Intervention Module 1 Participants in the intervention group will review six Weibo post screenshots each featuring a mock-up Chinese fact-checking extension The control group will view identical screenshots but without the fact-checking extension Half of these posts will include false information After viewing each post those in the intervention group will evaluate a statement related to the Weibo content and corresponding to one of the predefined b HPV vaccine knowledge Their responses will be 1 Correct 2 Incorrect or 3 I dont know considering both the post content and the fact-checking extensions findings Participants in the control group will assess the same statement based only on the post content with the same response options
3 Phase 3 Intervention Module 2 All participants will review four additional Weibo post screenshots including two containing false information to evaluate whether exposure to the mock-up fact-checking extension has improved the intervention groups ability to identify false information The same question format from Intervention Module 1 will be used for responses
4 Phase 4 Post-intervention Assessment All participants are required to fill out sections on c HPV vaccine awareness and confidence and d vaccine intentions
5 Phase 5 Intervention Module 3 All participants in both groups will be asked whether they use a mock-up fact-checking extension when viewing Weibo post screenshots If participants choose Yes they will view a Weibo post screenshot with the extension displayed if they choose No the extension will not be displayed The same question format from Intervention Module 1 will be used for responses This phase aims to assess participants behaviour regarding the use of the extension
6 Phase 6 User Experience Assessment All participants will complete the section e the user experience with a mock-up fact-checking extension
Following the completion of the experiment a debunking procedure will be conducted for participants in both the intervention and control groups This is to avoid any potential risks associated with the spread of misinformation on Weibo
Data analysis will employ Difference-in-Differences DID analysis multiple logistic regression and other suitable statistical methods to evaluate the effectiveness of the mock-up Chinese fact-checking extension
The sample size for this study was determined based on the two primary outcomes knowledge of the HPV vaccine and the ability to dispel misinformation A review of the existing literature suggests that the intention or confidence among Chinese parents to vaccinate their children with the HPV vaccine as well as their knowledge about the vaccine and capability to counteract misinformation typically ranges from 50 to 70 We assumed a baseline rate of 60 for both vaccine knowledge and misinformation discernment It is anticipated that exposure to educational interventions will increase these rates by 10 elevating them to 70 Using a significance level of 005 and a statistical power of 90 the required sample size was calculated to be a minimum of 473 participants per group To accommodate potential variability and to strengthen the robustness of the study 500 participants will be recruited for each group maintaining a 11 ratio This approach results in a total sample size of 1000 participants Such a sample size ensures that the study is sufficiently powered to detect a significant change in the outcomes of interest
In this study 11 mobile Weibo post screenshots were created covering a range of topics including infertility safety vaccine ingredients high-risk cervical cancer types regular check-ups transmission routes and others
The participants in both groups will complete a questionnaire consisting of six phases
1 Phase 1 Baseline Assessment Participants in both the intervention and control groups will complete a questionnaire covering a basic demographic information b HPV vaccine knowledge c HPV vaccine awareness and confidence and d vaccination intentions
2 Phase 2 Intervention Module 1 Participants in the intervention group will review six Weibo post screenshots each featuring a mock-up Chinese fact-checking extension The control group will view identical screenshots but without the fact-checking extension Half of these posts will include false information After viewing each post those in the intervention group will evaluate a statement related to the Weibo content and corresponding to one of the predefined b HPV vaccine knowledge Their responses will be 1 Correct 2 Incorrect or 3 I dont know considering both the post content and the fact-checking extensions findings Participants in the control group will assess the same statement based only on the post content with the same response options
3 Phase 3 Intervention Module 2 All participants will review four additional Weibo post screenshots including two containing false information to evaluate whether exposure to the mock-up fact-checking extension has improved the intervention groups ability to identify false information The same question format from Intervention Module 1 will be used for responses
4 Phase 4 Post-intervention Assessment All participants are required to fill out sections on c HPV vaccine awareness and confidence and d vaccine intentions
5 Phase 5 Intervention Module 3 All participants in both groups will be asked whether they use a mock-up fact-checking extension when viewing Weibo post screenshots If participants choose Yes they will view a Weibo post screenshot with the extension displayed if they choose No the extension will not be displayed The same question format from Intervention Module 1 will be used for responses This phase aims to assess participants behaviour regarding the use of the extension
6 Phase 6 User Experience Assessment All participants will complete the section e the user experience with a mock-up fact-checking extension
Following the completion of the experiment a debunking procedure will be conducted for participants in both the intervention and control groups This is to avoid any potential risks associated with the spread of misinformation on Weibo
Data analysis will employ Difference-in-Differences DID analysis multiple logistic regression and other suitable statistical methods to evaluate the effectiveness of the mock-up Chinese fact-checking extension
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None