Ignite Creation Date:
2024-05-11 @ 8:30 AM
Last Modification Date:
2024-10-26 @ 3:28 PM
Study NCT ID:
NCT06402734
Status:
COMPLETED
Last Update Posted:
2024-05-07
First Post:
2024-05-03
Brief Title:
Effects of Gluten-Free Diet on Nutritional Status in Celiac Patients
Sponsor:
Hacettepe University
Organization:
Hacettepe University
Study Overview
Official Title:
Effects of Gluten-Free Diet on Nutritional Status and Inflammation Parameters in Adult Celiac Patients
Status:
COMPLETED
Status Verified Date:
2024-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study examined the impact of a gluten-free diet on nutritional status and inflammation markers in adult celiac patients compared to a control group Twenty-six celiac patients and 26 healthy individuals participated Interviews dietary records anthropometric measurements and blood samples were collected After six weeks celiac patients showed improved adherence to the gluten-free diet and increased quality of life scores While initial micronutrient intake was lower in celiac patients it improved over the study period However there were no significant changes in inflammation markers
Detailed Description:
This study aimed to examine the effects of a gluten-free diet on the nutritional status anthropometric measurements and serum levels of interferon-gamma IFN-γ and interleukin-15 IL-15 in adult celiac patients comparing them with a control group A total of 26 celiac patients aged 18-64 years and 26 healthy individuals as the control group were included Face-to-face interviews were conducted to determine participants39 general characteristics dietary habits and physical activity status Additionally a retrospective 24-hour dietary recall and food frequency questionnaire were administered to assess dietary intake Anthropometric measurements and blood samples were collected during the interviews Celiac patients received education about the gluten-free diet and follow-up assessments were conducted six weeks later At the beginning 538 of celiac patients reported alwaysmostly adhering to the gluten-free diet which increased to 1000 after six weeks The total quality of life scores significantly increased in celiac patients after six weeks Initial serum IL-15 levels were similar between celiac and control groups whereas serum IFN-γ levels were significantly higher in celiac patients compared to the control group
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None