Ignite Creation Date:
2024-05-11 @ 8:30 AM
Last Modification Date:
2024-10-26 @ 3:28 PM
Study NCT ID:
NCT06402084
Status:
RECRUITING
Last Update Posted:
2024-05-07
First Post:
2024-05-02
Brief Title:
The Relationship Between Fatty Liver and Breast Cancer
Sponsor:
Samar Saad Abdelrahman
Organization:
Sohag University
Study Overview
Official Title:
The Relationship Between Fatty Liver and Breast Cancer
Status:
RECRUITING
Status Verified Date:
2024-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
clinicopathological result of a common is NAFLD alcoholic fatty liver disease-nNo 30 of -NAFLD affects 20 not caused by alcohol intake is chronic liver disease thatsuch as conditions spectrum of population and can be characterized by wide general et Chalasani steatosis by isolated intracellular fat deposition marked noninflammatory al 2012
homeostasis and egulation of hepatic cholesterol NAFLD occurs due to the dysr NAFLD is liver in triglycerides and free cholesterol free fatty acids accumulation ofabdominal and with insulin resistance diabetes mellitus metabolic syndrome associatedimplicated in the be can NAFLD that suggested reports the arge number ofL obesity kidney diseases as well as cancersf cardiovascular pulmonary and pathology o 2015 et al Arguello
their course of the Patients with breast cancer commonly develop NAFLD during 452-23 approximately cancer is disease The incidence of NAFLD in breast by influenced metabolic profile and is patients NAFLD seems to be associated with cardiovascular and resistance insulin causingand treatment breast cancer complications Lee et al 2017
modulators term estrogen inhibition with selective estrogen receptors-Long liver with tamoxifen fatty incidence of The s been reported to cause NAFLDha SERMsof NAFLD development in impact heT use an that for aromatase inhibitoruse is higher th et al Yang breast cancer patients after hormonal treatment has not yet been elucidated 6201
main and is aworldwide most common cancer in womenBreast cancer is the decreasing with has been cancer breast from ityortalM women in death cancer of causeIt is well known time given the advances in screening strategies and adjuvant treatments incidence of breast cancer is correlated with age and other risk factors such asthat the mutation family history of BRCA2 breast cancer gene2 or BRCA1gene1breast cancer alet Berry and hormonal factors chest the to breast cancer therapeutic radiation5200
Breast cancer is divided according to the hormone receptors into either hormone receptor-positive tumors which are estrogen receptor-positive ER-positive and progesterone receptor-positive PR-positive These tumors express hormone receptors This means they have a lot of hormone receptors Hormone receptor-negative tumors are estrogen receptor-negative ER-negative and progesterone receptor-negative PR-negative These tumors donot express hormone receptors This means they have few or no hormone receptors About 70 to 80 of newly diagnosed breast cancers are hormone receptor- al 2017 Wang et positive
homeostasis and egulation of hepatic cholesterol NAFLD occurs due to the dysr NAFLD is liver in triglycerides and free cholesterol free fatty acids accumulation ofabdominal and with insulin resistance diabetes mellitus metabolic syndrome associatedimplicated in the be can NAFLD that suggested reports the arge number ofL obesity kidney diseases as well as cancersf cardiovascular pulmonary and pathology o 2015 et al Arguello
their course of the Patients with breast cancer commonly develop NAFLD during 452-23 approximately cancer is disease The incidence of NAFLD in breast by influenced metabolic profile and is patients NAFLD seems to be associated with cardiovascular and resistance insulin causingand treatment breast cancer complications Lee et al 2017
modulators term estrogen inhibition with selective estrogen receptors-Long liver with tamoxifen fatty incidence of The s been reported to cause NAFLDha SERMsof NAFLD development in impact heT use an that for aromatase inhibitoruse is higher th et al Yang breast cancer patients after hormonal treatment has not yet been elucidated 6201
main and is aworldwide most common cancer in womenBreast cancer is the decreasing with has been cancer breast from ityortalM women in death cancer of causeIt is well known time given the advances in screening strategies and adjuvant treatments incidence of breast cancer is correlated with age and other risk factors such asthat the mutation family history of BRCA2 breast cancer gene2 or BRCA1gene1breast cancer alet Berry and hormonal factors chest the to breast cancer therapeutic radiation5200
Breast cancer is divided according to the hormone receptors into either hormone receptor-positive tumors which are estrogen receptor-positive ER-positive and progesterone receptor-positive PR-positive These tumors express hormone receptors This means they have a lot of hormone receptors Hormone receptor-negative tumors are estrogen receptor-negative ER-negative and progesterone receptor-negative PR-negative These tumors donot express hormone receptors This means they have few or no hormone receptors About 70 to 80 of newly diagnosed breast cancers are hormone receptor- al 2017 Wang et positive
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None