Ignite Creation Date:
2024-05-11 @ 8:31 AM
Last Modification Date:
2024-10-26 @ 3:29 PM
Study NCT ID:
NCT06406712
Status:
RECRUITING
Last Update Posted:
2024-06-05
First Post:
2024-05-06
Brief Title:
Retroclavicular Block in Vascular Surgey
Sponsor:
New Valley University
Organization:
New Valley University
Study Overview
Official Title:
Efficacy of Retroclavicular Dexamethasone With Bupivacaine in Patients Undergoing Upper Limb Vascular Surgeries
Status:
RECRUITING
Status Verified Date:
2024-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The retroclavicular coracoid approach for brachial plexus anesthesia is recognized for its facility and simplicity to perform
The block has been well described in the anesthesia community since it was first introduced by Hebbard and Royse in 2007 In 2017 Luftig first described the blocks use in the ED setting for a variety of indications Because of its different needle entry point the retro clavicular RCB approach offers an almost perpendicular needle-ultrasound US beam angle
The block has been well described in the anesthesia community since it was first introduced by Hebbard and Royse in 2007 In 2017 Luftig first described the blocks use in the ED setting for a variety of indications Because of its different needle entry point the retro clavicular RCB approach offers an almost perpendicular needle-ultrasound US beam angle
Detailed Description:
Regional anesthesia RA offers several advantages over general anesthesia GA for upper limb orthopedic surgery One of the advantages is the improvement in postoperative pain which leads to decreased use of postoperative opioids needs and reduces the recovery time for patients A variety of approaches for regional blockade for upper extremity surgery have been described
Dexamethasone is a corticosteroid drug that has been used as an adjuvant to reduce postoperative pain
The use of peri neural dexamethasone ie dexamethasone added to the local anesthesia solution as an adjuvant to peripheral nerve block to improve analgesia provided by local anesthetic alone Peri neural dexamethasone as an adjuvant to peripheral nerve block has been associated with faster onset of anesthesia longer duration of anesthesiaanalgesia decreased postoperative pain intensity and decreased postoperative analgesia requirements compared with local anaesthetic alone The exact mechanism by which dexamethasone reduces pain is not known The decrease in pain intensity and the prolonged analgesia attained with the use of perineural dexamethasone may be the result of a local or systemic action or both Dexamethasone may act locally on glucocorticosteroid receptors to induce vasoconstriction thereby decreasing systemic absorption of local anaesthetics Other potential mechanisms of action include suppression of C-fibre transmission of pain signals and direct action on the nerve cell to reduce neural discharge Dexamethasone may act systemically by reducing the inflammatory response caused by surgical tissue injury
Dexamethasone is a corticosteroid drug that has been used as an adjuvant to reduce postoperative pain
The use of peri neural dexamethasone ie dexamethasone added to the local anesthesia solution as an adjuvant to peripheral nerve block to improve analgesia provided by local anesthetic alone Peri neural dexamethasone as an adjuvant to peripheral nerve block has been associated with faster onset of anesthesia longer duration of anesthesiaanalgesia decreased postoperative pain intensity and decreased postoperative analgesia requirements compared with local anaesthetic alone The exact mechanism by which dexamethasone reduces pain is not known The decrease in pain intensity and the prolonged analgesia attained with the use of perineural dexamethasone may be the result of a local or systemic action or both Dexamethasone may act locally on glucocorticosteroid receptors to induce vasoconstriction thereby decreasing systemic absorption of local anaesthetics Other potential mechanisms of action include suppression of C-fibre transmission of pain signals and direct action on the nerve cell to reduce neural discharge Dexamethasone may act systemically by reducing the inflammatory response caused by surgical tissue injury
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None