Ignite Creation Date:
2024-05-11 @ 8:31 AM
Last Modification Date:
2024-10-26 @ 3:29 PM
Study NCT ID:
NCT06407128
Status:
RECRUITING
Last Update Posted:
2024-05-09
First Post:
2024-05-06
Brief Title:
Valvular Microbiota and Valvulopathy
Sponsor:
University Hospital Toulouse
Organization:
University Hospital Toulouse
Study Overview
Official Title:
Valvular Microbiota and Valvulopathy
Status:
RECRUITING
Status Verified Date:
2024-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
MICROVALV
Brief Summary:
Few teams in the world can reliably analyze tissue microbiota In this regard the present group has unique expertise in the analysis of blood and tissue microbiota the first to describe in 2011
Having a blood biomarker of this valve microbiota could help guide the therapeutic strategy before and after the intervention This study will be the first to test the hypothesis that the analysis of the blood microbiota makes it possible to detect the carriage of a tissue microbiota in patients undergoing aortic valve replacement AVR for degenerative aortic valve disease and should also lay the foundations for a prospective study intended to evaluate the impact of the blood and valve microbiota on the post-operative prognosis of these patients and the complications at one year This would be a first proof of concept of the role of the tissue microbiota in valvular degeneration linked to aging
Having a blood biomarker of this valve microbiota could help guide the therapeutic strategy before and after the intervention This study will be the first to test the hypothesis that the analysis of the blood microbiota makes it possible to detect the carriage of a tissue microbiota in patients undergoing aortic valve replacement AVR for degenerative aortic valve disease and should also lay the foundations for a prospective study intended to evaluate the impact of the blood and valve microbiota on the post-operative prognosis of these patients and the complications at one year This would be a first proof of concept of the role of the tissue microbiota in valvular degeneration linked to aging
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None