Ignite Creation Date:
2024-05-19 @ 5:33 PM
Last Modification Date:
2024-10-26 @ 3:29 PM
Study NCT ID:
NCT06411093
Status:
COMPLETED
Last Update Posted:
2024-05-13
First Post:
2024-05-08
Brief Title:
Efficacy and Safety of Kinesiology Tape Wrapping for Paronychia Induced by Epidermal Growth Factor Receptor Inhibitors
Sponsor:
Chang Gung Memorial Hospital
Organization:
Chang Gung Memorial Hospital
Study Overview
Official Title:
A Single-center Randomized Open-labelled Trial to Evaluate the Efficacy and Safety of the Kinesiology Tape for the Treatment of Paronychia Induced by Epidermal Growth Factor Receptor Inhibitors in Cancer Patients
Status:
COMPLETED
Status Verified Date:
2024-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Epidermal growth factor receptor inhibitorsEGFRIs have been applied in several common malignancies including advanced non-small cell lung cancer Paronychia is one of the most common cutaneous side effects characterized by inflamed granulation tissue around the nails leading to pain and reduced quality of life Despite available conventional therapies such as topical beta-blockers or chemical cauterization some patients still do not respond well Our previous pilot study suggested that adding Kinesiology tape wrapping to the conventional treatment may effectively improve pain and granulomas in patients with treatment-resistant EGFRI-related paronychia with good safety This study aims to evaluate the clinical efficacy and safety of using Kinesiology tape wrapping as an adjunct to conventional therapy for patients with EGFRI-related paronychia
Detailed Description:
In this study eligible patients with paronychia affecting their big toes will be included and randomized to receive a combination of Kinesiology tape wrapping and conventional treatment or conventional treatment alone for 3 months Patients are evaluated at baseline at 1 2 4 8 and 12 weeks after the initiation of the treatment These evaluations will occur at the outpatient department or through phone contact and photos taken by patients if they cannot visit in person Efficacy endpoints include pain numerical rating scale NRS and scoring system for paronychia related to oncologic treatments SPOT Besides any side effects will be recorded at each visit
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None