Ignite Creation Date:
2024-05-19 @ 5:34 PM
Last Modification Date:
2024-10-26 @ 3:29 PM
Study NCT ID:
NCT06411977
Status:
ACTIVE_NOT_RECRUITING
Last Update Posted:
2024-05-14
First Post:
2024-05-02
Brief Title:
Effect of Dietary Supplements on the Oral Microbiome
Sponsor:
University Center of Dental Medicine Switzerland
Organization:
University Center of Dental Medicine Switzerland
Study Overview
Official Title:
Multiband--Bracket Induced Qualitative and Quantitative Changes in the Oral Microbiome and Its Influence by Preventive Intervention Using Dietary Supplements
Status:
ACTIVE_NOT_RECRUITING
Status Verified Date:
2024-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The oral cavitys microbiome is a diverse community hosting over 700 bacterial species Due to its varied niches the oral cavity constitutes a highly complex environment where different microbes preferentially colonize distinct habitats
The aim of the study was to investigate the alteration of the oral microbiome during therapy with fixed orthodontic appliances using dietary supplements
The aim of the study was to investigate the alteration of the oral microbiome during therapy with fixed orthodontic appliances using dietary supplements
Detailed Description:
In the randomized clinical trial the effect of dietary supplements vegetable juice was investigated in patients treated with fixed orthodontic appliances Saliva tongue and subgingival samples were taken from each participant at three different time points TO before insertion of fixed orthodontic therapy T1 14 days after daily administration of lettuce juice T2 up to 6 months after washout Orthodontic patients without dietary intervention served as controls In addition clinical indices were examined Samples were analyzed by Illumina 16S rRNA sequencing and taxonomically assigned
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None