Ignite Creation Date:
2024-05-19 @ 5:34 PM
Last Modification Date:
2024-10-26 @ 3:29 PM
Study NCT ID:
NCT06416735
Status:
COMPLETED
Last Update Posted:
2024-05-16
First Post:
2023-09-04
Brief Title:
Natriuretic Effect of Amiloride in Relation to the Alpha Adducin Gene ADD-AMI RS4961 Variant
Sponsor:
Ospedale San Raffaele
Organization:
Ospedale San Raffaele
Study Overview
Official Title:
Natriruetic Effect of Amiloride in Relation to the Alpha Adducin Gene ADD-AMI RS4961 Variant
Status:
COMPLETED
Status Verified Date:
2024-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
ADD-AMI
Brief Summary:
The study is a non-pharmacological interventional single-center national non-randomised comparative and open label
Detailed Description:
The study is carried out to evaluate primarily the difference in the activity of the renal transporter ENaC through dosage of sodium through its inhibition with a single dose of Amiloride in hypertensive patients characterized by the polymorphism of alpha Adducin rs496 Its also aimed to see the difference in potassium and the change in systolic and diastolic blood pressure after amiloride administration
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
True
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None