Ignite Creation Date:
2024-06-16 @ 11:47 AM
Last Modification Date:
2024-10-26 @ 3:30 PM
Study NCT ID:
NCT06425406
Status:
RECRUITING
Last Update Posted:
2024-06-18
First Post:
2024-04-15
Brief Title:
Application of HFNC for the Prevention of Hypoxemia During Perioperative Anesthetic-induced Intubation in Children A Randomized Controlled Clinical Trial
Sponsor:
Henan Provincial Peoples Hospital
Organization:
Henan Provincial Peoples Hospital
Study Overview
Official Title:
Application of HFNC for the Prevention of Hypoxemia During Perioperative Anesthetic-induced Intubation in Children A Randomized Controlled Clinical Trial
Status:
RECRUITING
Status Verified Date:
2024-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Compared with adults children have higher metabolic needs and the airway is more likely to collapse Before tracheal intubation after anesthesia induction the patient s spontaneous breathing completely disappears At this critical stage the residual oxygen of the lung is consumed resulting in hypoxemia and atelectasis Therefore it is necessary to explore the best oxygenation strategy during intubation In addition ultrasound has become a common equipment in the operating room It has the advantages of portability repeatability and no radiation and can provide strong support for the diagnosis of gastric distension
Detailed Description:
At present hypoxia is still the main cause of complications and death during perioperative period Compared with adults children have lower functional residual volume and lower tolerance to hypoxia caused by apnea due to their special physiological and functional characteristics During anesthesia induction and tracheal intubation spontaneous breathing completely disappears At this critical stage hypoxemia is prone to occur which in turn causes various serious complications Mask ventilation may occur mask ventilation difficulties and flatulence since the introduction of nasal high-flow oxygen therapy HFNC into the operating room in 2015 its oxygenation method has been shown to be able to significantly improve blood oxygen when used alone in pre-oxygenation When tracheal intubation is performed HFNC can still maintain ventilation in the patient s nose so HFNC can combine the advantages of both masks to perform pre-oxygenation There are few studies on the effect of HFNC on apnea oxygenation in children in the operating room
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None