Ignite Creation Date:
2024-06-16 @ 11:47 AM
Last Modification Date:
2024-10-26 @ 3:30 PM
Study NCT ID:
NCT06424314
Status:
RECRUITING
Last Update Posted:
2024-07-09
First Post:
2024-05-16
Brief Title:
Exploration of Mechanisms for Weaning Failure
Sponsor:
The First Affiliated Hospital of Guangzhou Medical University
Organization:
The First Affiliated Hospital of Guangzhou Medical University
Study Overview
Official Title:
Changes in Respiratory Mechanics in Patients With Failed Ventilator Withdrawal
Status:
RECRUITING
Status Verified Date:
2024-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study is a prospective physiologic study The primary study population will be adult invasive tracheal intubated patients with COPD and investigators will collect relevant demographic data vital signs and baseline physiologic parameters of the patients prior to the spontaneous breathing testSBT
The participants will be divided into a successful withdrawal group and a failed withdrawal group according to the SBT outcome and the changes in the above parameters during SBT will be compared between the two groups
The participants will be divided into a successful withdrawal group and a failed withdrawal group according to the SBT outcome and the changes in the above parameters during SBT will be compared between the two groups
Detailed Description:
This observational study mainly include participants who had invasive mechanical ventilation for 48 h and are assessed to be ready for the SBT trialThe SBT approach is based on the low-level pressure support mode
Prior to the SBT trial baseline demographic and physiologic data of the participants will be collected and the participants will be divided into two groups based on the results of the SBT trial successful and unsuccessful and the physiologic changes during the SBT trial will be compared between the two groups respectively
Prior to the SBT trial baseline demographic and physiologic data of the participants will be collected and the participants will be divided into two groups based on the results of the SBT trial successful and unsuccessful and the physiologic changes during the SBT trial will be compared between the two groups respectively
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None